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A tri-specific killer engager against mesothelin targets NK cells towards lung cancer.
Kennedy PR, Vallera DA, Ettestad B, Hallstrom C, Kodal B, Todhunter DA, Bendzick L, Hinderlie P, Walker JT, Pulkrabek B, Pastan I, Kratzke RA, Fujioka N, Miller JS, Felices M. Kennedy PR, et al. Among authors: pastan i. Front Immunol. 2023 Feb 22;14:1060905. doi: 10.3389/fimmu.2023.1060905. eCollection 2023. Front Immunol. 2023. PMID: 36911670 Free PMC article.
Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers.
Skorupan N, Peer CJ, Zhang X, Choo-Wosoba H, Ahmad MI, Lee MJ, Rastogi S, Sato N, Yu Y, Pegna GJ, Steinberg SM, Kalsi SS, Cao L, Figg WD, Trepel JB, Pastan I, FitzGerald D, Alewine C. Skorupan N, et al. Among authors: pastan i. Front Oncol. 2024 Apr 19;14:1386190. doi: 10.3389/fonc.2024.1386190. eCollection 2024. Front Oncol. 2024. PMID: 38706610 Free PMC article.
Mesothelin expression in human lung cancer.
Ho M, Bera TK, Willingham MC, Onda M, Hassan R, FitzGerald D, Pastan I. Ho M, et al. Among authors: pastan i. Clin Cancer Res. 2007 Mar 1;13(5):1571-5. doi: 10.1158/1078-0432.CCR-06-2161. Clin Cancer Res. 2007. PMID: 17332303
Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer antigen 125.
Hassan R, Sharon E, Thomas A, Zhang J, Ling A, Miettinen M, Kreitman RJ, Steinberg SM, Hollevoet K, Pastan I. Hassan R, et al. Among authors: pastan i. Cancer. 2014 Nov 1;120(21):3311-9. doi: 10.1002/cncr.28875. Epub 2014 Jul 2. Cancer. 2014. PMID: 24989332 Free PMC article. Clinical Trial.
1,281 results