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Effect of ionizing radiation exposure on Trypanosoma cruzi ubiquitin-proteasome system.
Cerqueira PG, Passos-Silva DG, Vieira-da-Rocha JP, Mendes IC, de Oliveira KA, Oliveira CF, Vilela LF, Nagem RA, Cardoso J, Nardelli SC, Krieger MA, Franco GR, Macedo AM, Pena SD, Schenkman S, Gomes DA, Guerra-Sá R, Machado CR. Cerqueira PG, et al. Among authors: passos silva dg. Mol Biochem Parasitol. 2017 Mar;212:55-67. doi: 10.1016/j.molbiopara.2017.01.005. Epub 2017 Jan 27. Mol Biochem Parasitol. 2017. PMID: 28137628 Free article.
Characterization of the Trypanosoma cruzi Rad51 gene and its role in recombination events associated with the parasite resistance to ionizing radiation.
Regis-da-Silva CG, Freitas JM, Passos-Silva DG, Furtado C, Augusto-Pinto L, Pereira MT, DaRocha WD, Franco GR, Macedo AM, Hoffmann JS, Cazaux C, Pena SD, Teixeira SM, Machado CR. Regis-da-Silva CG, et al. Mol Biochem Parasitol. 2006 Oct;149(2):191-200. doi: 10.1016/j.molbiopara.2006.05.012. Epub 2006 Jun 21. Mol Biochem Parasitol. 2006. PMID: 16828179
Trypanosoma cruzi gene expression in response to gamma radiation.
Grynberg P, Passos-Silva DG, Mourão Mde M, Hirata R Jr, Macedo AM, Machado CR, Bartholomeu DC, Franco GR. Grynberg P, et al. Among authors: passos silva dg. PLoS One. 2012;7(1):e29596. doi: 10.1371/journal.pone.0029596. Epub 2012 Jan 11. PLoS One. 2012. PMID: 22247781 Free PMC article.
Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi.
Rajão MA, Furtado C, Alves CL, Passos-Silva DG, de Moura MB, Schamber-Reis BL, Kunrath-Lima M, Zuma AA, Vieira-da-Rocha JP, Garcia JB, Mendes IC, Pena SD, Macedo AM, Franco GR, de Souza-Pinto NC, de Medeiros MH, Cruz AK, Motta MC, Teixeira SM, Machado CR. Rajão MA, et al. Among authors: passos silva dg. Environ Mol Mutagen. 2014 May;55(4):309-21. doi: 10.1002/em.21839. Epub 2013 Dec 18. Environ Mol Mutagen. 2014. PMID: 24347026
The DNA damage response is developmentally regulated in the African trypanosome.
Vieira-da-Rocha JP, Passos-Silva DG, Mendes IC, Rocha EA, Gomes DA, Machado CR, McCulloch R. Vieira-da-Rocha JP, et al. Among authors: passos silva dg. DNA Repair (Amst). 2019 Jan;73:78-90. doi: 10.1016/j.dnarep.2018.11.005. Epub 2018 Nov 14. DNA Repair (Amst). 2019. PMID: 30470509 Free PMC article.
Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response.
Campos PC, Silva VG, Furtado C, Machado-Silva A, Darocha WD, Peloso EF, Gadelha FR, Medeiros MH, Lana Gde C, Chen Y, Barnes RL, Passos-Silva DG, McCulloch R, Machado CR, Teixeira SM. Campos PC, et al. Mol Biochem Parasitol. 2011 Mar;176(1):8-16. doi: 10.1016/j.molbiopara.2010.11.001. Epub 2010 Nov 10. Mol Biochem Parasitol. 2011. PMID: 21073906 Free PMC article.
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