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Heme catabolism by tumor-associated macrophages controls metastasis formation.
Consonni FM, Bleve A, Totaro MG, Storto M, Kunderfranco P, Termanini A, Pasqualini F, Alì C, Pandolfo C, Sgambelluri F, Grazia G, Santinami M, Maurichi A, Milione M, Erreni M, Doni A, Fabbri M, Gribaldo L, Rulli E, Soares MP, Torri V, Mortarini R, Anichini A, Sica A. Consonni FM, et al. Among authors: pasqualini f. Nat Immunol. 2021 May;22(5):595-606. doi: 10.1038/s41590-021-00921-5. Epub 2021 Apr 26. Nat Immunol. 2021. PMID: 33903766
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).
Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Vincenzo B, Pasqualini F, Vago L, Nebuloni M, Mantovani A, Sica A. Biswas SK, et al. Among authors: pasqualini f. Blood. 2006 Mar 1;107(5):2112-22. doi: 10.1182/blood-2005-01-0428. Epub 2005 Nov 3. Blood. 2006. PMID: 16269622 Free article.
The long pentraxin 3 is a soluble and cell-associated component of the human semen.
Doni A, Paffoni A, Nebuloni M, Ragni G, Pasqualini F, Valentino S, Bonetti S, Mantovani A, Somigliana E, Garlanda C. Doni A, et al. Among authors: pasqualini f. Int J Androl. 2009 Jun;32(3):255-64. doi: 10.1111/j.1365-2605.2007.00845.x. Epub 2007 Dec 30. Int J Androl. 2009. PMID: 18179560 Free article.
Divergent effects of hypoxia on dendritic cell functions.
Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A. Mancino A, et al. Among authors: pasqualini f. Blood. 2008 Nov 1;112(9):3723-34. doi: 10.1182/blood-2008-02-142091. Epub 2008 Aug 11. Blood. 2008. PMID: 18694997 Free article.
Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells.
Doni A, Mantovani G, Porta C, Tuckermann J, Reichardt HM, Kleiman A, Sironi M, Rubino L, Pasqualini F, Nebuloni M, Signorini S, Peri G, Sica A, Beck-Peccoz P, Bottazzi B, Mantovani A. Doni A, et al. Among authors: pasqualini f. J Biol Chem. 2008 Oct 31;283(44):29983-92. doi: 10.1074/jbc.M805631200. Epub 2008 Aug 14. J Biol Chem. 2008. PMID: 18703503 Free PMC article.
Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6.
Maina V, Cotena A, Doni A, Nebuloni M, Pasqualini F, Milner CM, Day AJ, Mantovani A, Garlanda C. Maina V, et al. Among authors: pasqualini f. J Leukoc Biol. 2009 Jul;86(1):123-32. doi: 10.1189/jlb.0608345. Epub 2009 Apr 23. J Leukoc Biol. 2009. PMID: 19389798 Free PMC article.
Role of macrophage targeting in the antitumor activity of trabectedin.
Germano G, Frapolli R, Belgiovine C, Anselmo A, Pesce S, Liguori M, Erba E, Uboldi S, Zucchetti M, Pasqualini F, Nebuloni M, van Rooijen N, Mortarini R, Beltrame L, Marchini S, Fuso Nerini I, Sanfilippo R, Casali PG, Pilotti S, Galmarini CM, Anichini A, Mantovani A, D'Incalci M, Allavena P. Germano G, et al. Among authors: pasqualini f. Cancer Cell. 2013 Feb 11;23(2):249-62. doi: 10.1016/j.ccr.2013.01.008. Cancer Cell. 2013. PMID: 23410977 Free article.
PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer.
Bonavita E, Gentile S, Rubino M, Maina V, Papait R, Kunderfranco P, Greco C, Feruglio F, Molgora M, Laface I, Tartari S, Doni A, Pasqualini F, Barbati E, Basso G, Galdiero MR, Nebuloni M, Roncalli M, Colombo P, Laghi L, Lambris JD, Jaillon S, Garlanda C, Mantovani A. Bonavita E, et al. Among authors: pasqualini f. Cell. 2015 Feb 12;160(4):700-714. doi: 10.1016/j.cell.2015.01.004. Cell. 2015. PMID: 25679762 Free article.
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