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BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation.
Campagne A, Lee MK, Zielinski D, Michaud A, Le Corre S, Dingli F, Chen H, Shahidian LZ, Vassilev I, Servant N, Loew D, Pasmant E, Postel-Vinay S, Wassef M, Margueron R. Campagne A, et al. Among authors: pasmant e. Nat Commun. 2019 Jan 21;10(1):348. doi: 10.1038/s41467-018-08255-x. Nat Commun. 2019. PMID: 30664650 Free PMC article.
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis.
Wassef M, Rodilla V, Teissandier A, Zeitouni B, Gruel N, Sadacca B, Irondelle M, Charruel M, Ducos B, Michaud A, Caron M, Marangoni E, Chavrier P, Le Tourneau C, Kamal M, Pasmant E, Vidaud M, Servant N, Reyal F, Meseure D, Vincent-Salomon A, Fre S, Margueron R. Wassef M, et al. Among authors: pasmant e. Genes Dev. 2015 Dec 15;29(24):2547-62. doi: 10.1101/gad.269522.115. Epub 2015 Dec 4. Genes Dev. 2015. PMID: 26637281 Free PMC article.
EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.
Wassef M, Luscan A, Aflaki S, Zielinski D, Jansen PWTC, Baymaz HI, Battistella A, Kersouani C, Servant N, Wallace MR, Romero P, Kosmider O, Just PA, Hivelin M, Jacques S, Vincent-Salomon A, Vermeulen M, Vidaud M, Pasmant E, Margueron R. Wassef M, et al. Among authors: pasmant e. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6075-6080. doi: 10.1073/pnas.1814634116. Epub 2019 Mar 13. Proc Natl Acad Sci U S A. 2019. PMID: 30867289 Free PMC article.
Phosphorylation of Merlin by Aurora A kinase appears necessary for mitotic progression.
Mandati V, Del Maestro L, Dingli F, Lombard B, Loew D, Molinie N, Romero S, Bouvard D, Louvard D, Gautreau AM, Pasmant E, Lallemand D. Mandati V, et al. Among authors: pasmant e. J Biol Chem. 2019 Aug 30;294(35):12992-13005. doi: 10.1074/jbc.RA118.006937. Epub 2019 Jul 11. J Biol Chem. 2019. PMID: 31296571 Free PMC article.
"MPNST Epigenetics"-Letter.
Wassef M, Pasmant E, Margueron R. Wassef M, et al. Among authors: pasmant e. Mol Cancer Res. 2019 Oct;17(10):2139. doi: 10.1158/1541-7786.MCR-19-0680. Mol Cancer Res. 2019. PMID: 31575727 No abstract available.
Identification of potential common genetic modifiers of neurofibromas: a genome-wide association study in 1333 patients with neurofibromatosis type 1.
Pacot L, Sabbagh A, Sohier P, Hadjadj D, Ye M, Boland-Auge A, Bacq-Daian D, Laurendeau I, Briand-Suleau A, Deleuze JF, Margueron R, Vidaud M, Ferkal S, Parfait B, Vidaud D; NF-France Network; Pasmant E, Wolkenstein P. Pacot L, et al. Among authors: pasmant e. Br J Dermatol. 2024 Jan 23;190(2):226-243. doi: 10.1093/bjd/ljad390. Br J Dermatol. 2024. PMID: 37831592
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