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Mesenchymal stem/stromal cell extracellular vesicles: From active principle to next generation drug delivery system.
Crivelli B, Chlapanidas T, Perteghella S, Lucarelli E, Pascucci L, Brini AT, Ferrero I, Marazzi M, Pessina A, Torre ML; Italian Mesenchymal Stem Cell Group (GISM). Crivelli B, et al. Among authors: pascucci l. J Control Release. 2017 Sep 28;262:104-117. doi: 10.1016/j.jconrel.2017.07.023. Epub 2017 Jul 20. J Control Release. 2017. PMID: 28736264 Review.
Mesenchymal stromal cells primed with Paclitaxel attract and kill leukaemia cells, inhibit angiogenesis and improve survival of leukaemia-bearing mice.
Pessina A, Coccè V, Pascucci L, Bonomi A, Cavicchini L, Sisto F, Ferrari M, Ciusani E, Crovace A, Falchetti ML, Zicari S, Caruso A, Navone S, Marfia G, Benetti A, Ceccarelli P, Parati E, Alessandri G. Pessina A, et al. Among authors: pascucci l. Br J Haematol. 2013 Mar;160(6):766-78. doi: 10.1111/bjh.12196. Epub 2013 Jan 7. Br J Haematol. 2013. PMID: 23293837 Free article.
Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery.
Pascucci L, Coccè V, Bonomi A, Ami D, Ceccarelli P, Ciusani E, Viganò L, Locatelli A, Sisto F, Doglia SM, Parati E, Bernardo ME, Muraca M, Alessandri G, Bondiolotti G, Pessina A. Pascucci L, et al. J Control Release. 2014 Oct 28;192:262-70. doi: 10.1016/j.jconrel.2014.07.042. Epub 2014 Jul 30. J Control Release. 2014. PMID: 25084218
Drug-releasing mesenchymal cells strongly suppress B16 lung metastasis in a syngeneic murine model.
Pessina A, Leonetti C, Artuso S, Benetti A, Dessy E, Pascucci L, Passeri D, Orlandi A, Berenzi A, Bonomi A, Coccè V, Ceserani V, Ferri A, Dossena M, Mazzuca P, Ciusani E, Ceccarelli P, Caruso A, Portolani N, Sisto F, Parati E, Alessandri G. Pessina A, et al. Among authors: pascucci l. J Exp Clin Cancer Res. 2015 Aug 13;34(1):82. doi: 10.1186/s13046-015-0200-3. J Exp Clin Cancer Res. 2015. PMID: 26264809 Free PMC article.
Gemcitabine-releasing mesenchymal stromal cells inhibit in vitro proliferation of human pancreatic carcinoma cells.
Bonomi A, Sordi V, Dugnani E, Ceserani V, Dossena M, Coccè V, Cavicchini L, Ciusani E, Bondiolotti G, Piovani G, Pascucci L, Sisto F, Alessandri G, Piemonti L, Parati E, Pessina A. Bonomi A, et al. Among authors: pascucci l. Cytotherapy. 2015 Dec;17(12):1687-95. doi: 10.1016/j.jcyt.2015.09.005. Epub 2015 Oct 21. Cytotherapy. 2015. PMID: 26481416
95 results