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Mitochondrial RNA modifications shape metabolic plasticity in metastasis.
Delaunay S, Pascual G, Feng B, Klann K, Behm M, Hotz-Wagenblatt A, Richter K, Zaoui K, Herpel E, Münch C, Dietmann S, Hess J, Benitah SA, Frye M. Delaunay S, et al. Among authors: pascual g. Nature. 2022 Jul;607(7919):593-603. doi: 10.1038/s41586-022-04898-5. Epub 2022 Jun 29. Nature. 2022. PMID: 35768510 Free PMC article.
Targeting metastasis-initiating cells through the fatty acid receptor CD36.
Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L, Benitah SA. Pascual G, et al. Nature. 2017 Jan 5;541(7635):41-45. doi: 10.1038/nature20791. Epub 2016 Dec 7. Nature. 2017. PMID: 27974793
L1CAM links regeneration to metastasis.
Pascual G, Benitah SA. Pascual G, et al. Nat Cancer. 2020 Jan;1(1):22-24. doi: 10.1038/s43018-019-0014-x. Nat Cancer. 2020. PMID: 35121841 No abstract available.
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis.
Ladanyi A, Mukherjee A, Kenny HA, Johnson A, Mitra AK, Sundaresan S, Nieman KM, Pascual G, Benitah SA, Montag A, Yamada SD, Abumrad NA, Lengyel E. Ladanyi A, et al. Among authors: pascual g. Oncogene. 2018 Apr;37(17):2285-2301. doi: 10.1038/s41388-017-0093-z. Epub 2018 Feb 5. Oncogene. 2018. PMID: 29398710 Free PMC article.
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma.
Choi JE, Sebastian C, Ferrer CM, Lewis CA, Sade-Feldman M, LaSalle T, Gonye A, Lopez BGC, Abdelmoula WM, Regan MS, Cetinbas M, Pascual G, Wojtkiewicz GR, Silveira GG, Boon R, Ross KN, Tirosh I, Saladi SV, Ellisen LW, Sadreyev RI, Benitah SA, Agar NYR, Hacohen N, Mostoslavsky R. Choi JE, et al. Among authors: pascual g. Nat Metab. 2021 Feb;3(2):182-195. doi: 10.1038/s42255-021-00350-6. Epub 2021 Feb 22. Nat Metab. 2021. PMID: 33619381 Free PMC article.
Dietary palmitic acid promotes a prometastatic memory via Schwann cells.
Pascual G, Domínguez D, Elosúa-Bayes M, Beckedorff F, Laudanna C, Bigas C, Douillet D, Greco C, Symeonidi A, Hernández I, Gil SR, Prats N, Bescós C, Shiekhattar R, Amit M, Heyn H, Shilatifard A, Benitah SA. Pascual G, et al. Nature. 2021 Nov;599(7885):485-490. doi: 10.1038/s41586-021-04075-0. Epub 2021 Nov 10. Nature. 2021. PMID: 34759321 Free article.
The circadian molecular clock creates epidermal stem cell heterogeneity.
Janich P, Pascual G, Merlos-Suárez A, Batlle E, Ripperger J, Albrecht U, Cheng HY, Obrietan K, Di Croce L, Benitah SA. Janich P, et al. Among authors: pascual g. Nature. 2011 Nov 9;480(7376):209-14. doi: 10.1038/nature10649. Nature. 2011. PMID: 22080954
VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma.
Lorenzo-Martín LF, Fernández-Parejo N, Menacho-Márquez M, Rodríguez-Fdez S, Robles-Valero J, Zumalave S, Fabbiano S, Pascual G, García-Pedrero JM, Abad A, García-Macías MC, González N, Lorenzano-Menna P, Pavón MA, González-Sarmiento R, Segrelles C, Paramio JM, Tubío JMC, Rodrigo JP, Benitah SA, Cuadrado M, Bustelo XR. Lorenzo-Martín LF, et al. Among authors: pascual g. Nat Commun. 2020 Sep 22;11(1):4788. doi: 10.1038/s41467-020-18524-3. Nat Commun. 2020. PMID: 32963234 Free PMC article.
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity.
Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA, Di Croce L. Ballaré C, et al. Among authors: pascual g. Nat Struct Mol Biol. 2012 Dec;19(12):1257-65. doi: 10.1038/nsmb.2434. Epub 2012 Oct 28. Nat Struct Mol Biol. 2012. PMID: 23104054 Free PMC article.
191 results