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PARP1 associates with R-loops to promote their resolution and genome stability.
Laspata N, Kaur P, Mersaoui SY, Muoio D, Liu ZS, Bannister MH, Nguyen HD, Curry C, Pascal JM, Poirier GG, Wang H, Masson JY, Fouquerel E. Laspata N, et al. Among authors: pascal jm. Nucleic Acids Res. 2023 Mar 21;51(5):2215-2237. doi: 10.1093/nar/gkad066. Nucleic Acids Res. 2023. PMID: 36794853 Free PMC article.
Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs.
Gagné JP, Ethier C, Defoy D, Bourassa S, Langelier MF, Riccio AA, Pascal JM, Moon KM, Foster LJ, Ning Z, Figeys D, Droit A, Poirier GG. Gagné JP, et al. Among authors: pascal jm. DNA Repair (Amst). 2015 Jun;30:68-79. doi: 10.1016/j.dnarep.2015.02.004. Epub 2015 Feb 19. DNA Repair (Amst). 2015. PMID: 25800440
Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks.
Caron MC, Sharma AK, O'Sullivan J, Myler LR, Ferreira MT, Rodrigue A, Coulombe Y, Ethier C, Gagné JP, Langelier MF, Pascal JM, Finkelstein IJ, Hendzel MJ, Poirier GG, Masson JY. Caron MC, et al. Among authors: pascal jm. Nat Commun. 2019 Jul 4;10(1):2954. doi: 10.1038/s41467-019-10741-9. Nat Commun. 2019. PMID: 31273204 Free PMC article.
CARM1 regulates replication fork speed and stress response by stimulating PARP1.
Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. Genois MM, et al. Among authors: pascal jm. Mol Cell. 2021 Feb 18;81(4):784-800.e8. doi: 10.1016/j.molcel.2020.12.010. Epub 2021 Jan 6. Mol Cell. 2021. PMID: 33412112 Free PMC article.
86 results