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Outcomes After Endovascular Therapy With Procedural Sedation vs General Anesthesia in Patients With Acute Ischemic Stroke: The AMETIS Randomized Clinical Trial.
Chabanne R, Geeraerts T, Begard M, Balança B, Rapido F, Degos V, Tavernier B, Molliex S, Velly L, Verdonk F, Lukaszewicz AC, Perrigault PF, Albucher JF, Cognard C, Guyot A, Fernandez C, Masgrau A, Moreno R, Ferrier A, Jaber S, Bazin JE, Pereira B, Futier E; ANARLF NetworkAMETIS Study Group. Chabanne R, et al. JAMA Neurol. 2023 May 1;80(5):474-483. doi: 10.1001/jamaneurol.2023.0413. JAMA Neurol. 2023. PMID: 37010829 Free PMC article. Clinical Trial.
PARP1 associates with R-loops to promote their resolution and genome stability.
Laspata N, Kaur P, Mersaoui SY, Muoio D, Liu ZS, Bannister MH, Nguyen HD, Curry C, Pascal JM, Poirier GG, Wang H, Masson JY, Fouquerel E. Laspata N, et al. Among authors: pascal jm. Nucleic Acids Res. 2023 Mar 21;51(5):2215-2237. doi: 10.1093/nar/gkad066. Nucleic Acids Res. 2023. PMID: 36794853 Free PMC article.
Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors.
Arnold MR, Langelier MF, Gartrell J, Kirby IT, Sanderson DJ, Bejan DS, Šileikytė J, Sundalam SK, Nagarajan S, Marimuthu P, Duell AK, Shelat AA, Pascal JM, Cohen MS. Arnold MR, et al. Among authors: pascal jm. Cell Chem Biol. 2022 Dec 15;29(12):1694-1708.e10. doi: 10.1016/j.chembiol.2022.11.006. Epub 2022 Dec 8. Cell Chem Biol. 2022. PMID: 36493759 Free article.
465 results