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A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization.
Pacini C, Duncan E, Gonçalves E, Gilbert J, Bhosle S, Horswell S, Karakoc E, Lightfoot H, Curry E, Muyas F, Bouaboula M, Pedamallu CS, Cortes-Ciriano I, Behan FM, Zalmas LP, Barthorpe A, Francies H, Rowley S, Pollard J, Beltrao P, Parts L, Iorio F, Garnett MJ. Pacini C, et al. Among authors: parts l. Cancer Cell. 2024 Feb 12;42(2):301-316.e9. doi: 10.1016/j.ccell.2023.12.016. Epub 2024 Jan 11. Cancer Cell. 2024. PMID: 38215750 Free article.
Optimized whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells.
Usluer S, Hallast P, Crepaldi L, Zhou Y, Urgo K, Dincer C, Su J, Noell G, Alasoo K, El Garwany O, Gerety SS, Newman B, Dovey OM, Parts L. Usluer S, et al. Among authors: parts l. Stem Cell Reports. 2023 May 9;18(5):1061-1074. doi: 10.1016/j.stemcr.2023.03.008. Epub 2023 Apr 6. Stem Cell Reports. 2023. PMID: 37028423 Free PMC article.
Pooled Genome-Scale CRISPR Screens in Single Cells.
Schraivogel D, Steinmetz LM, Parts L. Schraivogel D, et al. Among authors: parts l. Annu Rev Genet. 2023 Nov 27;57:223-244. doi: 10.1146/annurev-genet-072920-013842. Epub 2023 Aug 10. Annu Rev Genet. 2023. PMID: 37562410 Free article. Review.
Predicting base editing outcomes using position-specific sequence determinants.
Pallaseni A, Peets EM, Koeppel J, Weller J, Vanderstichele T, Ho UL, Crepaldi L, van Leeuwen J, Allen F, Parts L. Pallaseni A, et al. Among authors: parts l. Nucleic Acids Res. 2022 Apr 8;50(6):3551-3564. doi: 10.1093/nar/gkac161. Nucleic Acids Res. 2022. PMID: 35286377 Free PMC article.
87 results