Parsons R - Search Results

1

Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells.

Chen H, Kleinberger JW, Takane KK, Salim F, Fiaschi-Taesch N, Pappas K, Parsons R, Jiang J, Zhang Y, Liu H, Wang P, Bender AS, Frank SJ, Stewart AF. Chen H, et al. Among authors: parsons r. Diabetes. 2015 Nov;64(11):3784-97. doi: 10.2337/db15-0083. Epub 2015 Jul 9. Diabetes. 2015. PMID: 26159175 Free PMC article.

2

A secreted PTEN phosphatase that enters cells to alter signaling and survival.

Hopkins BD, Fine B, Steinbach N, Dendy M, Rapp Z, Shaw J, Pappas K, Yu JS, Hodakoski C, Mense S, Klein J, Pegno S, Sulis ML, Goldstein H, Amendolara B, Lei L, Maurer M, Bruce J, Canoll P, Hibshoosh H, Parsons R. Hopkins BD, et al. Among authors: parsons r. Science. 2013 Jul 26;341(6144):399-402. doi: 10.1126/science.1234907. Epub 2013 Jun 6. Science. 2013. PMID: 23744781 Free PMC article.

3

p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes.

Pappas K, Xu J, Zairis S, Resnick-Silverman L, Abate F, Steinbach N, Ozturk S, Saal LH, Su T, Cheung P, Schmidt H, Aaronson S, Hibshoosh H, Manfredi J, Rabadan R, Parsons R. Pappas K, et al. Among authors: parsons r. Mol Cancer Res. 2017 Aug;15(8):1051-1062. doi: 10.1158/1541-7786.MCR-17-0089. Epub 2017 May 8. Mol Cancer Res. 2017. PMID: 28483946 Free PMC article.

4

NOTCH and EZH2 collaborate to repress PTEN expression in breast cancer.

Pappas K, Martin TC, Wolfe AL, Nguyen CB, Su T, Jin J, Hibshoosh H, Parsons R. Pappas K, et al. Among authors: parsons r. Commun Biol. 2021 Mar 9;4(1):312. doi: 10.1038/s42003-021-01825-8. Commun Biol. 2021. PMID: 33750924 Free PMC article.

5

Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis.

Hodakoski C, Hopkins BD, Barrows D, Mense SM, Keniry M, Anderson KE, Kern PA, Hawkins PT, Stephens LR, Parsons R. Hodakoski C, et al. Among authors: parsons r. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):155-60. doi: 10.1073/pnas.1213773111. Epub 2013 Dec 23. Proc Natl Acad Sci U S A. 2014. PMID: 24367090 Free PMC article.

6

Analysis of intracellular PTEN signaling and secretion.

Hodakoski C, Fine B, Hopkins B, Parsons R. Hodakoski C, et al. Among authors: parsons r. Methods. 2015 May;77-78:164-71. doi: 10.1016/j.ymeth.2014.11.008. Epub 2014 Nov 15. Methods. 2015. PMID: 25462559 Free PMC article. Review.

7

Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.

Stratikopoulos EE, Dendy M, Szabolcs M, Khaykin AJ, Lefebvre C, Zhou MM, Parsons R. Stratikopoulos EE, et al. Among authors: parsons r. Cancer Cell. 2015 Jun 8;27(6):837-51. doi: 10.1016/j.ccell.2015.05.006. Cancer Cell. 2015. PMID: 26058079 Free PMC article.

8

Gab2-mediated signaling promotes melanoma metastasis.

Horst B, Gruvberger-Saal SK, Hopkins BD, Bordone L, Yang Y, Chernoff KA, Uzoma I, Schwipper V, Liebau J, Nowak NJ, Brunner G, Owens D, Rimm DL, Parsons R, Celebi JT. Horst B, et al. Among authors: parsons r. Am J Pathol. 2009 Apr;174(4):1524-33. doi: 10.2353/ajpath.2009.080543. Am J Pathol. 2009. PMID: 19342374 Free PMC article.

9

A new class of cancer-associated PTEN mutations defined by membrane translocation defects.

Nguyen HN, Yang JM Jr, Rahdar M, Keniry M, Swaney KF, Parsons R, Park BH, Sesaki H, Devreotes PN, Iijima M. Nguyen HN, et al. Among authors: parsons r. Oncogene. 2015 Jul;34(28):3737-43. doi: 10.1038/onc.2014.293. Epub 2014 Sep 29. Oncogene. 2015. PMID: 25263454 Free PMC article.

10

Molecular pathways: intercellular PTEN and the potential of PTEN restoration therapy.

Hopkins BD, Parsons RE. Hopkins BD, et al. Clin Cancer Res. 2014 Nov 1;20(21):5379-83. doi: 10.1158/1078-0432.CCR-13-2661. Clin Cancer Res. 2014. PMID: 25361917 Free PMC article. Review.

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