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Hydrogen peroxide-dependent oxidation of ERK2 within its D-recruitment site alters its substrate selection.
Postiglione AE, Adams LL, Ekhator ES, Odelade AE, Patwardhan S, Chaudhari M, Pardue AS, Kumari A, LeFever WA, Tornow OP, Kaoud TS, Neiswinger J, Jeong JS, Parsonage D, Nelson KJ, Kc DB, Furdui CM, Zhu H, Wommack AJ, Dalby KN, Dong M, Poole LB, Keyes JD, Newman RH. Postiglione AE, et al. Among authors: parsonage d. iScience. 2023 Sep 2;26(10):107817. doi: 10.1016/j.isci.2023.107817. eCollection 2023 Oct 20. iScience. 2023. PMID: 37744034 Free PMC article.
Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
Huynh MV, Parsonage D, Forshaw TE, Chirasani VR, Hobbs GA, Wu H, Lee J, Furdui CM, Poole LB, Campbell SL. Huynh MV, et al. Among authors: parsonage d. J Biol Chem. 2022 Aug;298(8):102186. doi: 10.1016/j.jbc.2022.102186. Epub 2022 Jun 24. J Biol Chem. 2022. PMID: 35753348 Free PMC article.
Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins.
Bolduc JA, Nelson KJ, Haynes AC, Lee J, Reisz JA, Graff AH, Clodfelter JE, Parsonage D, Poole LB, Furdui CM, Lowther WT. Bolduc JA, et al. Among authors: parsonage d. J Biol Chem. 2018 Jul 27;293(30):11901-11912. doi: 10.1074/jbc.RA117.001690. Epub 2018 Jun 8. J Biol Chem. 2018. PMID: 29884768 Free PMC article.
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