Parrill AL - Search Results

1

Design of anticancer lysophosphatidic acid agonists and antagonists.

Parrill AL. Parrill AL. Future Med Chem. 2014 May;6(8):871-83. doi: 10.4155/fmc.14.52. Future Med Chem. 2014. PMID: 24962280 Review.

2

Lysophosphatidic acid receptor agonists and antagonists (WO2010051053).

Parrill AL. Parrill AL. Expert Opin Ther Pat. 2011 Feb;21(2):281-6. doi: 10.1517/13543776.2011.539206. Epub 2011 Jan 11. Expert Opin Ther Pat. 2011. PMID: 21222547 Free PMC article.

3

Structure-based drug design identifies novel LPA3 antagonists.

Fells JI, Tsukahara R, Liu J, Tigyi G, Parrill AL. Fells JI, et al. Among authors: parrill al. Bioorg Med Chem. 2009 Nov 1;17(21):7457-64. doi: 10.1016/j.bmc.2009.09.022. Epub 2009 Sep 18. Bioorg Med Chem. 2009. PMID: 19800804 Free PMC article.

4

Optimization of a pipemidic acid autotaxin inhibitor.

Hoeglund AB, Bostic HE, Howard AL, Wanjala IW, Best MD, Baker DL, Parrill AL. Hoeglund AB, et al. Among authors: parrill al. J Med Chem. 2010 Feb 11;53(3):1056-66. doi: 10.1021/jm9012328. J Med Chem. 2010. PMID: 20041668

5

Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells.

Banerjee S, Norman DD, Lee SC, Parrill AL, Pham TC, Baker DL, Tigyi GJ, Miller DD. Banerjee S, et al. Among authors: parrill al. J Med Chem. 2017 Feb 23;60(4):1309-1324. doi: 10.1021/acs.jmedchem.6b01270. Epub 2017 Feb 10. J Med Chem. 2017. PMID: 28112925 Free PMC article.

6

Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands.

Durgam GG, Tsukahara R, Makarova N, Walker MD, Fujiwara Y, Pigg KR, Baker DL, Sardar VM, Parrill AL, Tigyi G, Miller DD. Durgam GG, et al. Among authors: parrill al. Bioorg Med Chem Lett. 2006 Feb;16(3):633-40. doi: 10.1016/j.bmcl.2005.10.031. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263282

7

Optical Control of Lysophosphatidic Acid Signaling.

Morstein J, Dacheux MA, Norman DD, Shemet A, Donthamsetti PC, Citir M, Frank JA, Schultz C, Isacoff EY, Parrill AL, Tigyi GJ, Trauner D. Morstein J, et al. Among authors: parrill al. J Am Chem Soc. 2020 Jun 17;142(24):10612-10616. doi: 10.1021/jacs.0c02154. Epub 2020 Jun 5. J Am Chem Soc. 2020. PMID: 32469525 Free PMC article.

8

Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells.

Fujiwara Y, Sardar V, Tokumura A, Baker D, Murakami-Murofushi K, Parrill A, Tigyi G. Fujiwara Y, et al. J Biol Chem. 2005 Oct 14;280(41):35038-50. doi: 10.1074/jbc.M504351200. Epub 2005 Aug 22. J Biol Chem. 2005. PMID: 16115890 Free article.

9

Identification of non-lipid LPA3 antagonists by virtual screening.

Fells JI, Tsukahara R, Fujiwara Y, Liu J, Perygin DH, Osborne DA, Tigyi G, Parrill AL. Fells JI, et al. Among authors: parrill al. Bioorg Med Chem. 2008 Jun 1;16(11):6207-17. doi: 10.1016/j.bmc.2008.04.035. Epub 2008 Apr 18. Bioorg Med Chem. 2008. PMID: 18467108 Free PMC article.

10

Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors.

Virag T, Elrod DB, Liliom K, Sardar VM, Parrill AL, Yokoyama K, Durgam G, Deng W, Miller DD, Tigyi G. Virag T, et al. Among authors: parrill al. Mol Pharmacol. 2003 May;63(5):1032-42. doi: 10.1124/mol.63.5.1032. Mol Pharmacol. 2003. PMID: 12695531

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