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Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha.
Gianni' M, Boldetti A, Guarnaccia V, Rambaldi A, Parrella E, Raska I Jr, Rochette-Egly C, Del Sal G, Rustighi A, Terao M, Garattini E. Gianni' M, et al. Among authors: parrella e. Cancer Res. 2009 Feb 1;69(3):1016-26. doi: 10.1158/0008-5472.CAN-08-2603. Epub 2009 Jan 20. Cancer Res. 2009. PMID: 19155306
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis.
Garattini E, Parrella E, Diomede L, Gianni' M, Kalac Y, Merlini L, Simoni D, Zanier R, Ferrara FF, Chiarucci I, Carminati P, Terao M, Pisano C. Garattini E, et al. Among authors: parrella e. Blood. 2004 Jan 1;103(1):194-207. doi: 10.1182/blood-2003-05-1577. Epub 2003 Sep 4. Blood. 2004. PMID: 12958071 Free article.
Phosphodiesterase IV inhibition by piclamilast potentiates the cytodifferentiating action of retinoids in myeloid leukemia cells. Cross-talk between the cAMP and the retinoic acid signaling pathways.
Parrella E, Gianni' M, Cecconi V, Nigro E, Barzago MM, Rambaldi A, Rochette-Egly C, Terao M, Garattini E. Parrella E, et al. J Biol Chem. 2004 Oct 1;279(40):42026-40. doi: 10.1074/jbc.M406530200. Epub 2004 Jul 28. J Biol Chem. 2004. PMID: 15292163 Free article.
Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamma and retinoid-independent pathways.
Parrella E, Giannì M, Fratelli M, Barzago MM, Raska I Jr, Diomede L, Kurosaki M, Pisano C, Carminati P, Merlini L, Dallavalle S, Tavecchio M, Rochette-Egly C, Terao M, Garattini E. Parrella E, et al. Mol Pharmacol. 2006 Sep;70(3):909-24. doi: 10.1124/mol.106.023614. Epub 2006 Jun 20. Mol Pharmacol. 2006. PMID: 16788091
Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models.
Rangan P, Lobo F, Parrella E, Rochette N, Morselli M, Stephen TL, Cremonini AL, Tagliafico L, Persia A, Caffa I, Monacelli F, Odetti P, Bonfiglio T, Nencioni A, Pigliautile M, Boccardi V, Mecocci P, Pike CJ, Cohen P, LaDu MJ, Pellegrini M, Xia K, Tran K, Ann B, Chowdhury D, Longo VD. Rangan P, et al. Among authors: parrella e. Cell Rep. 2022 Sep 27;40(13):111417. doi: 10.1016/j.celrep.2022.111417. Cell Rep. 2022. PMID: 36170815 Free PMC article.
29 results