Parplys AC - Search Results

1

Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines.

Subtil FSB, Gröbner C, Recknagel N, Parplys AC, Kohl S, Arenz A, Eberle F, Dikomey E, Engenhart-Cabillic R, Schötz U. Subtil FSB, et al. Among authors: parplys ac. Cancers (Basel). 2022 Jun 28;14(13):3160. doi: 10.3390/cancers14133160. Cancers (Basel). 2022. PMID: 35804930 Free PMC article.

2

DNA damage by X-rays and their impact on replication processes.

Parplys AC, Petermann E, Petersen C, Dikomey E, Borgmann K. Parplys AC, et al. Radiother Oncol. 2012 Mar;102(3):466-71. doi: 10.1016/j.radonc.2012.01.005. Epub 2012 Feb 11. Radiother Oncol. 2012. PMID: 22326574

3

High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.

Parplys AC, Seelbach JI, Becker S, Behr M, Wrona A, Jend C, Mansour WY, Joosse SA, Stuerzbecher HW, Pospiech H, Petersen C, Dikomey E, Borgmann K. Parplys AC, et al. Cell Cycle. 2015;14(19):3190-202. doi: 10.1080/15384101.2015.1055996. Cell Cycle. 2015. PMID: 26317153 Free PMC article.

4

Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner.

Rieckhoff J, Meyer F, Classen S, Zielinski A, Riepen B, Wikman H, Petersen C, Rothkamm K, Borgmann K, Parplys AC. Rieckhoff J, et al. Among authors: parplys ac. Cancers (Basel). 2020 Sep 29;12(10):2809. doi: 10.3390/cancers12102809. Cancers (Basel). 2020. PMID: 33003585 Free PMC article.

5

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response.

Wurster S, Hennes F, Parplys AC, Seelbach JI, Mansour WY, Zielinski A, Petersen C, Clauditz TS, Münscher A, Friedl AA, Borgmann K. Wurster S, et al. Among authors: parplys ac. Oncotarget. 2016 Mar 1;7(9):9732-41. doi: 10.18632/oncotarget.6947. Oncotarget. 2016. PMID: 26799421 Free PMC article.

6

Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities.

Struve N, Hoffer K, Weik AS, Riepen B, Krug L, Cetin MH, Burmester J, Ott L, Liebing J, Gatzemeier F, Müller-Goebel J, Gerbach M, Bußmann L, Parplys AC, Unger K, Mansour WY, Schüller U, Rieckmann T, Petersen C, Rothkamm K, Short SC, Kriegs M. Struve N, et al. Among authors: parplys ac. Neurooncol Adv. 2021 Dec 4;4(1):vdab180. doi: 10.1093/noajnl/vdab180. eCollection 2022 Jan-Dec. Neurooncol Adv. 2021. PMID: 35274102 Free PMC article.

7

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer.

Meyer F, Becker S, Classen S, Parplys AC, Mansour WY, Riepen B, Timm S, Ruebe C, Jasin M, Wikman H, Petersen C, Rothkamm K, Borgmann K. Meyer F, et al. Among authors: parplys ac. Cells. 2020 Jan 17;9(1):238. doi: 10.3390/cells9010238. Cells. 2020. PMID: 31963582 Free PMC article.

8

Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability.

Trego KS, Groesser T, Davalos AR, Parplys AC, Zhao W, Nelson MR, Hlaing A, Shih B, Rydberg B, Pluth JM, Tsai MS, Hoeijmakers JHJ, Sung P, Wiese C, Campisi J, Cooper PK. Trego KS, et al. Among authors: parplys ac. Mol Cell. 2016 Feb 18;61(4):535-546. doi: 10.1016/j.molcel.2015.12.026. Epub 2016 Jan 28. Mol Cell. 2016. PMID: 26833090 Free PMC article.

9

Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2^-/- mice.

Barikbin R, Berkhout L, Bolik J, Schmidt-Arras D, Ernst T, Ittrich H, Adam G, Parplys A, Casar C, Krech T, Karimi K, Sass G, Tiegs G. Barikbin R, et al. Sci Rep. 2018 Nov 2;8(1):16238. doi: 10.1038/s41598-018-33233-0. Sci Rep. 2018. PMID: 30389969 Free PMC article.

10

DNA Repair.

Borgmann K, Köcher S, Kriegs M, Mansour WY, Parplys AC, Rieckmann T, Rothkamm K. Borgmann K, et al. Among authors: parplys ac. Recent Results Cancer Res. 2016;198:1-24. doi: 10.1007/978-3-662-49651-0_1. Recent Results Cancer Res. 2016. PMID: 27318679 Review.

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