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Microenvironmental pH is a key factor for exosome traffic in tumor cells.
Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, De Milito A, Coscia C, Iessi E, Logozzi M, Molinari A, Colone M, Tatti M, Sargiacomo M, Fais S. Parolini I, et al. J Biol Chem. 2009 Dec 4;284(49):34211-22. doi: 10.1074/jbc.M109.041152. Epub 2009 Sep 30. J Biol Chem. 2009. PMID: 19801663 Free PMC article.
Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules.
Boussadia Z, Lamberti J, Mattei F, Pizzi E, Puglisi R, Zanetti C, Pasquini L, Fratini F, Fantozzi L, Felicetti F, Fecchi K, Raggi C, Sanchez M, D'Atri S, Carè A, Sargiacomo M, Parolini I. Boussadia Z, et al. Among authors: parolini i. J Exp Clin Cancer Res. 2018 Oct 5;37(1):245. doi: 10.1186/s13046-018-0915-z. J Exp Clin Cancer Res. 2018. PMID: 30290833 Free PMC article.
Inhibition of cholesterol transport impairs Cav-1 trafficking and small extracellular vesicles secretion, promoting amphisome formation in melanoma cells.
Peruzzu D, Boussadia Z, Fratini F, Spadaro F, Bertuccini L, Sanchez M, Carollo M, Matarrese P, Falchi M, Iosi F, Raggi C, Parolini I, Carè A, Sargiacomo M, Gagliardi MC, Fecchi K. Peruzzu D, et al. Among authors: parolini i. Traffic. 2023 Feb;24(2):76-94. doi: 10.1111/tra.12878. Epub 2023 Jan 6. Traffic. 2023. PMID: 36519961 Free article.
41 results