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Development of inhibitors of heterotrimeric Gαi subunits.
Appleton KM, Bigham KJ, Lindsey CC, Hazard S, Lirjoni J, Parnham S, Hennig M, Peterson YK. Appleton KM, et al. Among authors: parnham s. Bioorg Med Chem. 2014 Jul 1;22(13):3423-34. doi: 10.1016/j.bmc.2014.04.035. Epub 2014 Apr 26. Bioorg Med Chem. 2014. PMID: 24818958 Free PMC article.
Assignment of the absolute configuration of hepatoprotective highly oxygenated triterpenoids using X-ray, ECD, NMR J-based configurational analysis and HSQC overlay experiments.
Wang X, Liu J, Pandey P, Chen J, Fronczek FR, Parnham S, Qi X, Doerksen RJ, Ferreira D, Sun H, Li S, Hamann MT. Wang X, et al. Among authors: parnham s. Biochim Biophys Acta Gen Subj. 2017 Dec;1861(12):3089-3095. doi: 10.1016/j.bbagen.2017.09.001. Epub 2017 Sep 15. Biochim Biophys Acta Gen Subj. 2017. PMID: 28919469 Free PMC article.
Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics.
Brinson RG, Marino JP, Delaglio F, Arbogast LW, Evans RM, Kearsley A, Gingras G, Ghasriani H, Aubin Y, Pierens GK, Jia X, Mobli M, Grant HG, Keizer DW, Schweimer K, Ståhle J, Widmalm G, Zartler ER, Lawrence CW, Reardon PN, Cort JR, Xu P, Ni F, Yanaka S, Kato K, Parnham SR, Tsao D, Blomgren A, Rundlöf T, Trieloff N, Schmieder P, Ross A, Skidmore K, Chen K, Keire D, Freedberg DI, Suter-Stahel T, Wider G, Ilc G, Plavec J, Bradley SA, Baldisseri DM, Sforça ML, Zeri ACM, Wei JY, Szabo CM, Amezcua CA, Jordan JB, Wikström M. Brinson RG, et al. Among authors: parnham sr. MAbs. 2019 Jan;11(1):94-105. doi: 10.1080/19420862.2018.1544454. Epub 2018 Dec 22. MAbs. 2019. PMID: 30570405 Free PMC article.
Development and optimization of OspC chimeritope vaccinogens for Lyme disease.
Izac JR, O'Bier NS, Oliver LD Jr, Camire AC, Earnhart CG, LeBlanc Rhodes DV, Young BF, Parnham SR, Davies C, Marconi RT. Izac JR, et al. Among authors: parnham sr. Vaccine. 2020 Feb 18;38(8):1915-1924. doi: 10.1016/j.vaccine.2020.01.027. Epub 2020 Jan 17. Vaccine. 2020. PMID: 31959423 Free PMC article.
21 results