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Targeted Deletion of Hepatocyte Abca1 Increases Plasma HDL (High-Density Lipoprotein) Reverse Cholesterol Transport via the LDL (Low-Density Lipoprotein) Receptor.
Bashore AC, Liu M, Key CC, Boudyguina E, Wang X, Carroll CM, Sawyer JK, Mullick AE, Lee RG, Macauley SL, Parks JS. Bashore AC, et al. Among authors: parks js. Arterioscler Thromb Vasc Biol. 2019 Sep;39(9):1747-1761. doi: 10.1161/ATVBAHA.119.312382. Epub 2019 Jun 6. Arterioscler Thromb Vasc Biol. 2019. PMID: 31167565 Free PMC article.
Exploiting three-dimensional human hepatic constructs to investigate the impact of rs174537 on fatty acid metabolism.
Kirk LM, Waits CMK, Bashore AC, Dosso B, Meyers AK, Renaldo AC, DePalma TJ, Simms KN, Hauser N, Chuang Key CC, McCall CE, Parks JS, Sergeant S, Langefeld CD, Skardal A, Rahbar E. Kirk LM, et al. Among authors: parks js. PLoS One. 2022 Jan 20;17(1):e0262173. doi: 10.1371/journal.pone.0262173. eCollection 2022. PLoS One. 2022. PMID: 35051193 Free PMC article.
Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis.
Brown JM, Chung S, Sawyer JK, Degirolamo C, Alger HM, Nguyen T, Zhu X, Duong MN, Wibley AL, Shah R, Davis MA, Kelley K, Wilson MD, Kent C, Parks JS, Rudel LL. Brown JM, et al. Among authors: parks js. Circulation. 2008 Sep 30;118(14):1467-75. doi: 10.1161/CIRCULATIONAHA.108.793182. Epub 2008 Sep 15. Circulation. 2008. PMID: 18794388 Free PMC article.
Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis.
Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS. Key CC, et al. Among authors: parks js. Cell Rep. 2017 Jun 6;19(10):2116-2129. doi: 10.1016/j.celrep.2017.05.032. Cell Rep. 2017. PMID: 28591582 Free PMC article.
Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.
Brown JM, Chung S, Sawyer JK, Degirolamo C, Alger HM, Nguyen TM, Zhu X, Duong MN, Brown AL, Lord C, Shah R, Davis MA, Kelley K, Wilson MD, Madenspacher J, Fessler MB, Parks JS, Rudel LL. Brown JM, et al. Among authors: parks js. Arterioscler Thromb Vasc Biol. 2010 Jan;30(1):24-30. doi: 10.1161/ATVBAHA.109.198036. Epub 2009 Oct 15. Arterioscler Thromb Vasc Biol. 2010. PMID: 19834103 Free PMC article.
CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action.
Lord CC, Betters JL, Ivanova PT, Milne SB, Myers DS, Madenspacher J, Thomas G, Chung S, Liu M, Davis MA, Lee RG, Crooke RM, Graham MJ, Parks JS, Brasaemle DL, Fessler MB, Brown HA, Brown JM. Lord CC, et al. Among authors: parks js. Diabetes. 2012 Feb;61(2):355-63. doi: 10.2337/db11-0994. Epub 2012 Jan 6. Diabetes. 2012. PMID: 22228714 Free PMC article.
An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.
Ma L, Murea M, Snipes JA, Marinelarena A, Krüger J, Hicks PJ, Langberg KA, Bostrom MA, Cooke JN, Suzuki D, Babazono T, Uzu T, Tang SC, Mondal AK, Sharma NK, Kobes S, Antinozzi PA, Davis M, Das SK, Rasouli N, Kern PA, Shores NJ, Rudel LL, Blüher M, Stumvoll M, Bowden DW, Maeda S, Parks JS, Kovacs P, Hanson RL, Baier LJ, Elbein SC, Freedman BI. Ma L, et al. Among authors: parks js. PLoS One. 2013;8(2):e56193. doi: 10.1371/journal.pone.0056193. Epub 2013 Feb 27. PLoS One. 2013. PMID: 23460794 Free PMC article.
306 results