Parkinson EK - Search Results

1

A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype.

Melling GE, Flannery SE, Abidin SA, Clemmens H, Prajapati P, Hinsley EE, Hunt S, Catto JWF, Coletta RD, Mellone M, Thomas GJ, Parkinson EK, Prime SS, Paterson IC, Buttle DJ, Lambert DW. Melling GE, et al. Among authors: parkinson ek. Carcinogenesis. 2018 May 28;39(6):798-807. doi: 10.1093/carcin/bgy032. Carcinogenesis. 2018. PMID: 29506142 Free article.

2

Dysregulation of autocrine TGF-beta isoform production and ligand responses in human tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts.

Fahey MS, Paterson IC, Stone A, Collier AJ, Heung YL, Davies M, Patel V, Parkinson EK, Prime SS. Fahey MS, et al. Among authors: parkinson ek. Br J Cancer. 1996 Oct;74(7):1074-80. doi: 10.1038/bjc.1996.492. Br J Cancer. 1996. PMID: 8855977 Free PMC article.

3

Early genetic and functional events in the pathogenesis of oral cancer.

Prime SS, Eveson JW, Guest PG, Parkinson EK, Paterson IC. Prime SS, et al. Among authors: parkinson ek. Radiat Oncol Investig. 1997;5(3):93-6. doi: 10.1002/(sici)1520-6823(1997)5:3<93::aid-roi1>3.0.co;2-d. Radiat Oncol Investig. 1997. PMID: 9303062 Review.

4

Decreased expression of TGF-beta cell surface receptors during progression of human oral squamous cell carcinoma.

Paterson IC, Matthews JB, Huntley S, Robinson CM, Fahey M, Parkinson EK, Prime SS. Paterson IC, et al. Among authors: parkinson ek. J Pathol. 2001 Apr;193(4):458-67. doi: 10.1002/1096-9896(2000)9999:9999<::AID-PATH822>3.0.CO;2-V. J Pathol. 2001. PMID: 11276004

5

TGF-beta1 acts as a tumor suppressor of human malignant keratinocytes independently of Smad 4 expression and ligand-induced G(1) arrest.

Paterson IC, Davies M, Stone A, Huntley S, Smith E, Pring M, Eveson JW, Robinson CM, Parkinson EK, Prime SS. Paterson IC, et al. Among authors: parkinson ek. Oncogene. 2002 Feb 28;21(10):1616-24. doi: 10.1038/sj.onc.1205217. Oncogene. 2002. PMID: 11896591

6

Dysregulated TGF-beta1-induced Smad signalling occurs as a result of defects in multiple components of the TGF-beta signalling pathway in human head and neck carcinoma cell lines.

Pring M, Prime S, Parkinson EK, Paterson I. Pring M, et al. Among authors: parkinson ek. Int J Oncol. 2006 May;28(5):1279-85. Int J Oncol. 2006. PMID: 16596245

7

Fibroblast gene expression profile reflects the stage of tumour progression in oral squamous cell carcinoma.

Lim KP, Cirillo N, Hassona Y, Wei W, Thurlow JK, Cheong SC, Pitiyage G, Parkinson EK, Prime SS. Lim KP, et al. Among authors: parkinson ek. J Pathol. 2011 Mar;223(4):459-69. doi: 10.1002/path.2841. Epub 2011 Jan 17. J Pathol. 2011. PMID: 21294120

8

Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases.

Pitiyage GN, Slijepcevic P, Gabrani A, Chianea YG, Lim KP, Prime SS, Tilakaratne WM, Fortune F, Parkinson EK. Pitiyage GN, et al. Among authors: parkinson ek. J Pathol. 2011 Apr;223(5):604-17. doi: 10.1002/path.2839. Epub 2011 Feb 21. J Pathol. 2011. PMID: 21341274

9

Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs -1 and -2) in fibroblasts are early indicators of oral sub-mucous fibrosis and ageing.

Pitiyage GN, Lim KP, Gemenitzidis E, Teh MT, Waseem A, Prime SS, Tilakaratne WM, Fortune F, Parkinson EK. Pitiyage GN, et al. Among authors: parkinson ek. J Oral Pathol Med. 2012 Jul;41(6):454-62. doi: 10.1111/j.1600-0714.2012.01129.x. Epub 2012 Mar 3. J Oral Pathol Med. 2012. PMID: 22385081

10

Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β.

Hassona Y, Cirillo N, Lim KP, Herman A, Mellone M, Thomas GJ, Pitiyage GN, Parkinson EK, Prime SS. Hassona Y, et al. Among authors: parkinson ek. Carcinogenesis. 2013 Jun;34(6):1286-95. doi: 10.1093/carcin/bgt035. Epub 2013 Jan 27. Carcinogenesis. 2013. PMID: 23358854

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