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Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease.
Phelan J, Gomez-Gonzalez PJ, Andreu N, Omae Y, Toyo-Oka L, Yanai H, Miyahara R, Nedsuwan S, de Sessions PF, Campino S, Sallah N, Parkhill J, Smittipat N, Palittapongarnpim P, Mushiroda T, Kubo M, Tokunaga K, Mahasirimongkol S, Hibberd ML, Clark TG. Phelan J, et al. Among authors: parkhill j. Nat Commun. 2023 Feb 1;14(1):549. doi: 10.1038/s41467-023-36282-w. Nat Commun. 2023. PMID: 36725857 Free PMC article.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG. Cole ST, et al. Among authors: parkhill j. Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159. Nature. 1998. PMID: 9634230
Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing.
Clark TG, Mallard K, Coll F, Preston M, Assefa S, Harris D, Ogwang S, Mumbowa F, Kirenga B, O'Sullivan DM, Okwera A, Eisenach KD, Joloba M, Bentley SD, Ellner JJ, Parkhill J, Jones-López EC, McNerney R. Clark TG, et al. Among authors: parkhill j. PLoS One. 2013 Dec 11;8(12):e83012. doi: 10.1371/journal.pone.0083012. eCollection 2013. PLoS One. 2013. PMID: 24349420 Free PMC article. Clinical Trial.
PolyTB: a genomic variation map for Mycobacterium tuberculosis.
Coll F, Preston M, Guerra-Assunção JA, Hill-Cawthorn G, Harris D, Perdigão J, Viveiros M, Portugal I, Drobniewski F, Gagneux S, Glynn JR, Pain A, Parkhill J, McNerney R, Martin N, Clark TG. Coll F, et al. Among authors: parkhill j. Tuberculosis (Edinb). 2014 May;94(3):346-54. doi: 10.1016/j.tube.2014.02.005. Epub 2014 Feb 15. Tuberculosis (Edinb). 2014. PMID: 24637013 Free PMC article.
Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis.
Bos KI, Harkins KM, Herbig A, Coscolla M, Weber N, Comas I, Forrest SA, Bryant JM, Harris SR, Schuenemann VJ, Campbell TJ, Majander K, Wilbur AK, Guichon RA, Wolfe Steadman DL, Cook DC, Niemann S, Behr MA, Zumarraga M, Bastida R, Huson D, Nieselt K, Young D, Parkhill J, Buikstra JE, Gagneux S, Stone AC, Krause J. Bos KI, et al. Among authors: parkhill j. Nature. 2014 Oct 23;514(7523):494-7. doi: 10.1038/nature13591. Epub 2014 Aug 20. Nature. 2014. PMID: 25141181 Free PMC article.
Recurrence due to relapse or reinfection with Mycobacterium tuberculosis: a whole-genome sequencing approach in a large, population-based cohort with a high HIV infection prevalence and active follow-up.
Guerra-Assunção JA, Houben RM, Crampin AC, Mzembe T, Mallard K, Coll F, Khan P, Banda L, Chiwaya A, Pereira RP, McNerney R, Harris D, Parkhill J, Clark TG, Glynn JR. Guerra-Assunção JA, et al. Among authors: parkhill j. J Infect Dis. 2015 Apr 1;211(7):1154-63. doi: 10.1093/infdis/jiu574. Epub 2014 Oct 21. J Infect Dis. 2015. PMID: 25336729 Free PMC article.
Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis.
Weinert LA, Chaudhuri RR, Wang J, Peters SE, Corander J, Jombart T, Baig A, Howell KJ, Vehkala M, Välimäki N, Harris D, Chieu TT, Van Vinh Chau N, Campbell J, Schultsz C, Parkhill J, Bentley SD, Langford PR, Rycroft AN, Wren BW, Farrar J, Baker S, Hoa NT, Holden MT, Tucker AW, Maskell DJ; BRaDP1T Consortium. Weinert LA, et al. Among authors: parkhill j. Nat Commun. 2015 Mar 31;6:6740. doi: 10.1038/ncomms7740. Nat Commun. 2015. PMID: 25824154 Free PMC article.
Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi.
Glynn JR, Guerra-Assunção JA, Houben RM, Sichali L, Mzembe T, Mwaungulu LK, Mwaungulu JN, McNerney R, Khan P, Parkhill J, Crampin AC, Clark TG. Glynn JR, et al. Among authors: parkhill j. PLoS One. 2015 Jul 16;10(7):e0132840. doi: 10.1371/journal.pone.0132840. eCollection 2015. PLoS One. 2015. PMID: 26181760 Free PMC article.
745 results