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Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.
Arredouani A, Ruas M, Collins SC, Parkesh R, Clough F, Pillinger T, Coltart G, Rietdorf K, Royle A, Johnson P, Braun M, Zhang Q, Sones W, Shimomura K, Morgan AJ, Lewis AM, Chuang KT, Tunn R, Gadea J, Teboul L, Heister PM, Tynan PW, Bellomo EA, Rutter GA, Rorsman P, Churchill GC, Parrington J, Galione A. Arredouani A, et al. Among authors: parkesh r. J Biol Chem. 2015 Aug 28;290(35):21376-92. doi: 10.1074/jbc.M115.671248. Epub 2015 Jul 7. J Biol Chem. 2015. PMID: 26152717 Free PMC article.
NAADP controls cross-talk between distinct Ca2+ stores in the heart.
Macgregor A, Yamasaki M, Rakovic S, Sanders L, Parkesh R, Churchill GC, Galione A, Terrar DA. Macgregor A, et al. Among authors: parkesh r. J Biol Chem. 2007 May 18;282(20):15302-11. doi: 10.1074/jbc.M611167200. Epub 2007 Mar 26. J Biol Chem. 2007. PMID: 17387177 Free article.
Identification of a chemical probe for NAADP by virtual screening.
Naylor E, Arredouani A, Vasudevan SR, Lewis AM, Parkesh R, Mizote A, Rosen D, Thomas JM, Izumi M, Ganesan A, Galione A, Churchill GC. Naylor E, et al. Among authors: parkesh r. Nat Chem Biol. 2009 Apr;5(4):220-6. doi: 10.1038/nchembio.150. Epub 2009 Feb 22. Nat Chem Biol. 2009. PMID: 19234453 Free PMC article.
Synthesis and use of cell-permeant cyclic ADP-ribose.
Rosen D, Bloor-Young D, Squires J, Parkesh R, Waters G, Vasudevan SR, Lewis AM, Churchill GC. Rosen D, et al. Among authors: parkesh r. Biochem Biophys Res Commun. 2012 Feb 10;418(2):353-8. doi: 10.1016/j.bbrc.2012.01.025. Epub 2012 Jan 17. Biochem Biophys Res Commun. 2012. PMID: 22274607
Discovery of Mycobacterium tuberculosis α-1,4-glucan branching enzyme (GlgB) inhibitors by structure- and ligand-based virtual screening.
Dkhar HK, Gopalsamy A, Loharch S, Kaur A, Bhutani I, Saminathan K, Bhagyaraj E, Chandra V, Swaminathan K, Agrawal P, Parkesh R, Gupta P. Dkhar HK, et al. Among authors: parkesh r. J Biol Chem. 2015 Jan 2;290(1):76-89. doi: 10.1074/jbc.M114.589200. Epub 2014 Nov 10. J Biol Chem. 2015. PMID: 25384979 Free PMC article.
41 results