Parker PJ - Search Results

1

Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non-Small-Cell Lung Cancer.

Sánchez-Magraner L, Gumuzio J, Miles J, Quimi N, Martínez Del Prado P, Abad-Villar MT, Pikabea F, Ortega L, Etxezarraga C, Martín-Algarra S, Lozano MD, Saiz-Camin M, Egurrola-Izquierdo M, Barredo-Santamaría I, Saiz-López A, Gomez-Mediavilla J, Segues-Merino N, Juaristi-Abaunz MA, Urruticoechea A, Geraedts EJ, van Elst K, Claessens NJM, Italiano A, Applebee CJ, Del Castillo S, Evans C, Aguirre F, Parker PJ, Calleja V. Sánchez-Magraner L, et al. Among authors: parker pj. J Clin Oncol. 2023 May 10;41(14):2561-2570. doi: 10.1200/JCO.22.01748. Epub 2023 Feb 23. J Clin Oncol. 2023. PMID: 36821809 Free PMC article.

2

Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer.

Kong A, Leboucher P, Leek R, Calleja V, Winter S, Harris A, Parker PJ, Larijani B. Kong A, et al. Among authors: parker pj. Cancer Res. 2006 Mar 1;66(5):2834-43. doi: 10.1158/0008-5472.CAN-05-2994. Cancer Res. 2006. PMID: 16510606 Free article.

3

HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.

Kong A, Calleja V, Leboucher P, Harris A, Parker PJ, Larijani B. Kong A, et al. Among authors: parker pj. PLoS One. 2008 Aug 6;3(8):e2881. doi: 10.1371/journal.pone.0002881. PLoS One. 2008. PMID: 18682844 Free PMC article.

4

Acute regulation of PDK1 by a complex interplay of molecular switches.

Calleja V, Laguerre M, de Las Heras-Martinez G, Parker PJ, Requejo-Isidro J, Larijani B. Calleja V, et al. Among authors: parker pj. Biochem Soc Trans. 2014 Oct;42(5):1435-40. doi: 10.1042/BST20140222. Biochem Soc Trans. 2014. PMID: 25233428 Review.

5

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma.

Miles J, Applebee CJ, Leboucher P, Lopez-Fernandez S, Lee DJ, Guarch R, Ward S, Parker PJ, López JI, Larijani B. Miles J, et al. Among authors: parker pj. BBA Clin. 2017 Oct 13;8:97-102. doi: 10.1016/j.bbacli.2017.10.002. eCollection 2017 Dec. BBA Clin. 2017. PMID: 29296589 Free PMC article.

6

High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment.

Sánchez-Magraner L, Miles J, Baker CL, Applebee CJ, Lee DJ, Elsheikh S, Lashin S, Withers K, Watts AG, Parry R, Edmead C, Lopez JI, Mehta R, Italiano A, Ward SG, Parker PJ, Larijani B. Sánchez-Magraner L, et al. Among authors: parker pj. Cancer Res. 2020 Oct 1;80(19):4244-4257. doi: 10.1158/0008-5472.CAN-20-1117. Epub 2020 Aug 27. Cancer Res. 2020. PMID: 32855204

7

Quantification of biomarker functionality predicts patient outcomes.

Larijani B, Miles J, Ward SG, Parker PJ. Larijani B, et al. Among authors: parker pj. Br J Cancer. 2021 May;124(10):1618-1620. doi: 10.1038/s41416-021-01291-3. Epub 2021 Mar 15. Br J Cancer. 2021. PMID: 33723395 Free PMC article.

8

The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta.

Iturrioz X, Durgan J, Calleja V, Larijani B, Okuda H, Whelan R, Parker PJ. Iturrioz X, et al. Among authors: parker pj. Biochem J. 2006 Jul 1;397(1):109-20. doi: 10.1042/BJ20060354. Biochem J. 2006. PMID: 16669786 Free PMC article.

9

Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting.

Fili N, Calleja V, Woscholski R, Parker PJ, Larijani B. Fili N, et al. Among authors: parker pj. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15473-8. doi: 10.1073/pnas.0607040103. Epub 2006 Oct 9. Proc Natl Acad Sci U S A. 2006. PMID: 17030795 Free PMC article.

10

Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo.

Calleja V, Alcor D, Laguerre M, Park J, Vojnovic B, Hemmings BA, Downward J, Parker PJ, Larijani B. Calleja V, et al. Among authors: parker pj. PLoS Biol. 2007 Apr;5(4):e95. doi: 10.1371/journal.pbio.0050095. PLoS Biol. 2007. PMID: 17407381 Free PMC article.

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