Parker A - Search Results

1

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells.

Powell N, Pantazi E, Pavlidis P, Tsakmaki A, Li K, Yang F, Parker A, Pin C, Cozzetto D, Minns D, Stolarczyk E, Saveljeva S, Mohamed R, Lavender P, Afzali B, Digby-Bell J, Tjir-Li T, Kaser A, Friedman J, MacDonald TT, Bewick GA, Lord GM. Powell N, et al. Among authors: parker a. Gut. 2020 Mar;69(3):578-590. doi: 10.1136/gutjnl-2019-318483. Epub 2019 Dec 2. Gut. 2020. PMID: 31792136 Free PMC article. Review.

2

An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium.

Pin C, Parker A, Gunning AP, Ohta Y, Johnson IT, Carding SR, Sato T. Pin C, et al. Among authors: parker a. Integr Biol (Camb). 2015 Feb;7(2):213-28. doi: 10.1039/c4ib00236a. Integr Biol (Camb). 2015. PMID: 25537618 Free article.

3

Host-microbe interaction in the gastrointestinal tract.

Parker A, Lawson MAE, Vaux L, Pin C. Parker A, et al. Environ Microbiol. 2018 Jul;20(7):2337-2353. doi: 10.1111/1462-2920.13926. Epub 2017 Nov 10. Environ Microbiol. 2018. PMID: 28892253 Free PMC article. Review.

4

Chronic TNFα-driven injury delays cell migration to villi in the intestinal epithelium.

Muraro D, Parker A, Vaux L, Filippi S, Almet AA, Fletcher AG, Watson AJM, Pin C, Maini PK, Byrne HM. Muraro D, et al. Among authors: parker a. J R Soc Interface. 2018 Aug;15(145):20180037. doi: 10.1098/rsif.2018.0037. J R Soc Interface. 2018. PMID: 30068555 Free PMC article.

5

Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation.

Parker A, Vaux L, Patterson AM, Modasia A, Muraro D, Fletcher AG, Byrne HM, Maini PK, Watson AJM, Pin C. Parker A, et al. Cell Death Dis. 2019 Feb 6;10(2):108. doi: 10.1038/s41419-018-1275-5. Cell Death Dis. 2019. PMID: 30728350 Free PMC article.

6

Human resident gut microbe Bacteroides thetaiotaomicron regulates colonic neuronal innervation and neurogenic function.

Aktar R, Parkar N, Stentz R, Baumard L, Parker A, Goldson A, Brion A, Carding S, Blackshaw A, Peiris M. Aktar R, et al. Among authors: parker a. Gut Microbes. 2020 Nov 1;11(6):1745-1757. doi: 10.1080/19490976.2020.1766936. Epub 2020 Jun 9. Gut Microbes. 2020. PMID: 32515657 Free PMC article.

7

Homeostasis, injury, and recovery dynamics at multiple scales in a self-organizing mouse intestinal crypt.

Gall L, Duckworth C, Jardi F, Lammens L, Parker A, Bianco A, Kimko H, Pritchard DM, Pin C. Gall L, et al. Among authors: parker a. Elife. 2023 Dec 8;12:e85478. doi: 10.7554/eLife.85478. Elife. 2023. PMID: 38063302 Free PMC article.

8

Details unfold: the endoplasmic reticulum stress response in intestinal inflammation and cancer.

Parker A, Watson AJ. Parker A, et al. Gastroenterology. 2014 Aug;147(2):531-3. doi: 10.1053/j.gastro.2014.06.013. Epub 2014 Jun 20. Gastroenterology. 2014. PMID: 24953624 No abstract available.

9

Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi.

Parker A, Maclaren OJ, Fletcher AG, Muraro D, Kreuzaler PA, Byrne HM, Maini PK, Watson AJ, Pin C. Parker A, et al. FASEB J. 2017 Feb;31(2):636-649. doi: 10.1096/fj.201601002. Epub 2016 Oct 20. FASEB J. 2017. PMID: 27811059 Free PMC article.

This methodology can be applied to interrogate intestinal epithelial dynamics and characterize situations in which processes involved in cell turnover become uncoupled, including pharmacological treatments and disease models.-Parker, A., Maclaren, O. J., Fletcher, …

This methodology can be applied to interrogate intestinal epithelial dynamics and characterize situations in which processes involved in cel …

10

A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium.

Maclaren OJ, Parker A, Pin C, Carding SR, Watson AJM, Fletcher AG, Byrne HM, Maini PK. Maclaren OJ, et al. Among authors: parker a. PLoS Comput Biol. 2017 Jul 28;13(7):e1005688. doi: 10.1371/journal.pcbi.1005688. eCollection 2017 Jul. PLoS Comput Biol. 2017. PMID: 28753601 Free PMC article.

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