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Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform.
Chiuppesi F, Salazar MD, Contreras H, Nguyen VH, Martinez J, Park Y, Nguyen J, Kha M, Iniguez A, Zhou Q, Kaltcheva T, Levytskyy R, Ebelt ND, Kang TH, Wu X, Rogers TF, Manuel ER, Shostak Y, Diamond DJ, Wussow F. Chiuppesi F, et al. Among authors: park y. Nat Commun. 2020 Nov 30;11(1):6121. doi: 10.1038/s41467-020-19819-1. Nat Commun. 2020. PMID: 33257686 Free PMC article.
Synthetic Multiantigen MVA Vaccine COH04S1 Protects Against SARS-CoV-2 in Syrian Hamsters and Non-Human Primates.
Chiuppesi F, Nguyen VH, Park Y, Contreras H, Karpinski V, Faircloth K, Nguyen J, Kha M, Johnson D, Martinez J, Iniguez A, Zhou Q, Kaltcheva T, Frankel P, Kar S, Sharma A, Andersen H, Lewis MG, Shostak Y, Wussow F, Diamond DJ. Chiuppesi F, et al. Among authors: park y. bioRxiv [Preprint]. 2021 Sep 15:2021.09.15.460487. doi: 10.1101/2021.09.15.460487. bioRxiv. 2021. PMID: 34545366 Free PMC article. Updated. Preprint.
Successful outcome of pre-engraftment COVID-19 in an HCT patient: impact of targeted therapies and cellular immunity.
Pourhassan H, La Rosa C, Chiuppesi F, Puing A, Aldoss I, Park Y, Zhou Q, Karpinski V, Faircloth K, Kaltcheva T, Johnson D, Francisco SO, Zaia JA, Nakamura R, Al Malki MM, Diamond DJ, Dadwal SS, Forman SJ. Pourhassan H, et al. Among authors: park y. Blood Adv. 2022 Mar 22;6(6):1645-1650. doi: 10.1182/bloodadvances.2021006282. Blood Adv. 2022. PMID: 35008104 Free PMC article.
Synthetic multiantigen MVA vaccine COH04S1 protects against SARS-CoV-2 in Syrian hamsters and non-human primates.
Chiuppesi F, Nguyen VH, Park Y, Contreras H, Karpinski V, Faircloth K, Nguyen J, Kha M, Johnson D, Martinez J, Iniguez A, Zhou Q, Kaltcheva T, Frankel P, Kar S, Sharma A, Andersen H, Lewis MG, Shostak Y, Wussow F, Diamond DJ. Chiuppesi F, et al. Among authors: park y. NPJ Vaccines. 2022 Jan 21;7(1):7. doi: 10.1038/s41541-022-00436-6. NPJ Vaccines. 2022. PMID: 35064109 Free PMC article.
Safety and immunogenicity of a synthetic multiantigen modified vaccinia virus Ankara-based COVID-19 vaccine (COH04S1): an open-label and randomised, phase 1 trial.
Chiuppesi F, Zaia JA, Frankel PH, Stan R, Drake J, Williams B, Acosta AM, Francis K, Taplitz RA, Dickter JK, Dadwal S, Puing AG, Nanayakkara DD, Ash P, Cui Y, Contreras H, La Rosa C, Tiemann K, Park Y, Medina J, Iniguez A, Zhou Q, Karpinski V, Johnson D, Faircloth K, Kaltcheva T, Nguyen J, Kha M, Nguyen VH, Francisco SO, Grifoni A, Wong A, Sette A, Wussow F, Diamond DJ. Chiuppesi F, et al. Among authors: park y. Lancet Microbe. 2022 Apr;3(4):e252-e264. doi: 10.1016/S2666-5247(22)00027-1. Epub 2022 Mar 9. Lancet Microbe. 2022. PMID: 35287430 Free PMC article. Clinical Trial.
COH04S1 and beta sequence-modified vaccine protect hamsters from SARS-CoV-2 variants.
Wussow F, Kha M, Faircloth K, Nguyen VH, Iniguez A, Martinez J, Park Y, Nguyen J, Kar S, Andersen H, Lewis MG, Chiuppesi F, Diamond DJ. Wussow F, et al. Among authors: park y. iScience. 2022 Jun 17;25(6):104457. doi: 10.1016/j.isci.2022.104457. Epub 2022 May 23. iScience. 2022. PMID: 35634578 Free PMC article.
Vaccine-induced spike- and nucleocapsid-specific cellular responses maintain potent cross-reactivity to SARS-CoV-2 Delta and Omicron variants.
Chiuppesi F, Zaia JA, Faircloth K, Johnson D, Ly M, Karpinski V, La Rosa C, Drake J, Marcia J, Acosta AM, Dempsey S, Taplitz RA, Zhou Q, Park Y, Ortega Francisco S, Kaltcheva T, Frankel PH, Rosen S, Wussow F, Dadwal S, Diamond DJ. Chiuppesi F, et al. Among authors: park y. iScience. 2022 Aug 19;25(8):104745. doi: 10.1016/j.isci.2022.104745. Epub 2022 Jul 11. iScience. 2022. PMID: 35846380 Free PMC article.
Adoptive transfer of functional SARS-COV-2-specific immunity from donor graft to hematopoietic stem cell transplant recipients.
La Rosa C, Chiuppesi F, Park Y, Gendzekhadze K, Zhou Q, Faircloth K, Kaltcheva T, Johnson D, Ortega Francisco S, Amanam I, Otoukesh S, Pullarkat VA, Nakamura R, Diamond DJ, Forman SJ, Al Malki MM. La Rosa C, et al. Among authors: park y. Am J Hematol. 2022 Nov;97(11):E404-E407. doi: 10.1002/ajh.26691. Epub 2022 Sep 2. Am J Hematol. 2022. PMID: 36053823 Free PMC article. No abstract available.
Hematopoietic stem cell donor vaccination with cytomegalovirus triplex augments frequencies of functional and durable cytomegalovirus-specific T cells in the recipient: A novel strategy to limit antiviral prophylaxis.
La Rosa C, Aldoss I, Park Y, Yang D, Zhou Q, Gendzekhadze K, Kaltcheva T, Rida W, Dempsey S, Arslan S, Artz A, Ball B, Nikolaenko L, Pullarkat VA, Nakamura R, Diamond DJ. La Rosa C, et al. Among authors: park y. Am J Hematol. 2023 Apr;98(4):588-597. doi: 10.1002/ajh.26824. Epub 2023 Jan 11. Am J Hematol. 2023. PMID: 36594185 Free PMC article.
Functional SARS-CoV-2-specific T cells of donor origin in allogeneic stem cell transplant recipients of a T-cell-replete infusion: A prospective observational study.
La Rosa C, Chiuppesi F, Park Y, Zhou Q, Yang D, Gendzekhadze K, Ly M, Li J, Kaltcheva T, Ortega Francisco S, Gutierrez MA, Ali H, Otoukesh S, Amanam I, Salhotra A, Pullarkat VA, Aldoss I, Rosenzweig M, Aribi AM, Stein AS, Marcucci G, Dadwal SS, Nakamura R, Forman SJ, Al Malki MM, Diamond DJ. La Rosa C, et al. Among authors: park y. Front Immunol. 2023 Mar 3;14:1114131. doi: 10.3389/fimmu.2023.1114131. eCollection 2023. Front Immunol. 2023. PMID: 36936918 Free PMC article.
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