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Sirt3, mitochondrial ROS, ageing, and carcinogenesis.
Park SH, Ozden O, Jiang H, Cha YI, Pennington JD, Aykin-Burns N, Spitz DR, Gius D, Kim HS. Park SH, et al. Int J Mol Sci. 2011;12(9):6226-39. doi: 10.3390/ijms12096226. Epub 2011 Sep 23. Int J Mol Sci. 2011. PMID: 22016654 Free PMC article. Review.
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress.
Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JD, van der Meer R, Nguyen P, Savage J, Owens KM, Vassilopoulos A, Ozden O, Park SH, Singh KK, Abdulkadir SA, Spitz DR, Deng CX, Gius D. Kim HS, et al. Among authors: park sh. Cancer Cell. 2010 Jan 19;17(1):41-52. doi: 10.1016/j.ccr.2009.11.023. Cancer Cell. 2010. PMID: 20129246 Free PMC article.
SIRT2 directs the replication stress response through CDK9 deacetylation.
Zhang H, Park SH, Pantazides BG, Karpiuk O, Warren MD, Hardy CW, Duong DM, Park SJ, Kim HS, Vassilopoulos A, Seyfried NT, Johnsen SA, Gius D, Yu DS. Zhang H, et al. Among authors: park sj, park sh. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13546-51. doi: 10.1073/pnas.1301463110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898190 Free PMC article.
Transcriptional activation of p21(WAF¹/CIP¹) is mediated by increased DNA binding activity and increased interaction between p53 and Sp1 via phosphorylation during replicative senescence of human embryonic fibroblasts.
Kim HS, Heo JI, Park SH, Shin JY, Kang HJ, Kim MJ, Kim SC, Kim J, Park JB, Lee JY. Kim HS, et al. Among authors: park jb, park sh. Mol Biol Rep. 2014;41(4):2397-408. doi: 10.1007/s11033-014-3094-9. Epub 2014 Jan 21. Mol Biol Rep. 2014. PMID: 24445528
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