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JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
Pennel KAF, Hatthakarnkul P, Wood CS, Lian GY, Al-Badran SSF, Quinn JA, Legrini A, Inthagard J, Alexander PG, van Wyk H, Kurniawan A, Hashmi U, Gillespie MA, Mills M, Ammar A, Hay J, Andersen D, Nixon C, Rebus S, Chang DK, Kelly C, Harkin A, Graham J, Church D, Tomlinson I, Saunders M, Iveson T, Lannagan TRM, Jackstadt R, Maka N, Horgan PG, Roxburgh CSD, Sansom OJ, McMillan DC, Steele CW, Jamieson NB, Park JH, Roseweir AK, Edwards J. Pennel KAF, et al. Among authors: park jh. J Exp Clin Cancer Res. 2024 Mar 1;43(1):64. doi: 10.1186/s13046-024-02958-4. J Exp Clin Cancer Res. 2024. PMID: 38424636 Free PMC article.
Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer.
Roseweir AK, Park JH, Hoorn ST, Powell AG, Aherne S, Roxburgh CS, McMillan DC, Horgan PG, Ryan E, Sheahan K, Vermeulen L, Paul J, Harkin A, Graham J, Sansom O, Church DN, Tomlinson I, Saunders M, Iveson TJ, Edwards J. Roseweir AK, et al. Among authors: park jh. J Pathol Clin Res. 2020 Oct;6(4):283-296. doi: 10.1002/cjp2.171. Epub 2020 May 13. J Pathol Clin Res. 2020. PMID: 32401426 Free PMC article.
The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer.
Alexander PG, Roseweir AK, Pennel KAF, van Wyk HC, Powell AGMT, McMillan DC, Horgan PG, Kelly C, Hay J, Sansom O, Harkin A, Roxburgh CSD, Graham J, Church DN, Tomlinson I, Saunders M, Iveson TJ, Edwards J, Park JH. Alexander PG, et al. Among authors: park jh. Br J Cancer. 2021 Feb;124(4):786-796. doi: 10.1038/s41416-020-01168-x. Epub 2020 Nov 23. Br J Cancer. 2021. PMID: 33223535 Free PMC article.
Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer.
Al-Badran SS, Grant L, Campo MV, Inthagard J, Pennel K, Quinn J, Konanahalli P, Hayman L, Horgan PG, McMillan DC, Roxburgh CS, Roseweir A, Park JH, Edwards J. Al-Badran SS, et al. Among authors: park jh. J Pathol Clin Res. 2021 Mar;7(2):121-134. doi: 10.1002/cjp2.193. Epub 2020 Dec 18. J Pathol Clin Res. 2021. PMID: 33338327 Free PMC article.
CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer.
Pennel KA, Quinn JA, Nixon C, Inthagard J, van Wyk HC, Chang D, Rebus S; GPOL Group; Hay J, Maka NN, Roxburgh CS, Horgan PG, McMillan DC, Park JH, Roseweir AK, Steele CW, Edwards J. Pennel KA, et al. Among authors: park jh. J Pathol Clin Res. 2022 Nov;8(6):509-520. doi: 10.1002/cjp2.290. Epub 2022 Jul 25. J Pathol Clin Res. 2022. PMID: 35879507 Free PMC article.
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