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Lrig1-expression confers suppressive function to CD4+ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis.
Moon JS, Ho CC, Park JH, Park K, Shin BY, Lee SH, Sequeira I, Mun CH, Shin JS, Kim JH, Kim BS, Noh JW, Lee ES, Son JY, Kim Y, Lee Y, Cho H, So S, Park J, Choi E, Oh JW, Lee SW, Morio T, Watt FM, Seong RH, Lee SK. Moon JS, et al. Among authors: park jh, park k, park j. Nat Commun. 2023 Sep 4;14(1):5382. doi: 10.1038/s41467-023-40986-4. Nat Commun. 2023. PMID: 37666819 Free PMC article.
Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation.
Choi JM, Shin JH, Sohn MH, Harding MJ, Park JH, Tobiasova Z, Kim DY, Maher SE, Chae WJ, Park SH, Lee CG, Lee SK, Bothwell AL. Choi JM, et al. Among authors: park jh, park sh. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18575-80. doi: 10.1073/pnas.1000400107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937878 Free PMC article.
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production.
Chun H, Im H, Kang YJ, Kim Y, Shin JH, Won W, Lim J, Ju Y, Park YM, Kim S, Lee SE, Lee J, Woo J, Hwang Y, Cho H, Jo S, Park JH, Kim D, Kim DY, Seo JS, Gwag BJ, Kim YS, Park KD, Kaang BK, Cho H, Ryu H, Lee CJ. Chun H, et al. Among authors: park jh, park kd, park ym. Nat Neurosci. 2020 Dec;23(12):1555-1566. doi: 10.1038/s41593-020-00735-y. Epub 2020 Nov 16. Nat Neurosci. 2020. PMID: 33199896
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