Park J - Search Results

1

De novo design of tyrosine and serine kinase-driven protein switches.

Woodall NB, Weinberg Z, Park J, Busch F, Johnson RS, Feldbauer MJ, Murphy M, Ahlrichs M, Yousif I, MacCoss MJ, Wysocki VH, El-Samad H, Baker D. Woodall NB, et al. Among authors: park j. Nat Struct Mol Biol. 2021 Sep;28(9):762-770. doi: 10.1038/s41594-021-00649-8. Epub 2021 Sep 13. Nat Struct Mol Biol. 2021. PMID: 34518698 Free PMC article.

2

Orthogonal control of mean and variability of endogenous genes in a human cell line.

Bonny AR, Fonseca JP, Park JE, El-Samad H. Bonny AR, et al. Nat Commun. 2021 Jan 12;12(1):292. doi: 10.1038/s41467-020-20467-8. Nat Commun. 2021. PMID: 33436569 Free PMC article.

3

The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade.

Davis-Smyth T, Chen H, Park J, Presta LG, Ferrara N. Davis-Smyth T, et al. Among authors: park j. EMBO J. 1996 Sep 16;15(18):4919-27. EMBO J. 1996. PMID: 8890165 Free PMC article.

4

Synthetic group A streptogramin antibiotics that overcome Vat resistance.

Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT, van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray B, Jacobson MP, Mühle E, Chesneau O, Fraser JS, Seiple IB. Li Q, et al. Among authors: park je. Nature. 2020 Oct;586(7827):145-150. doi: 10.1038/s41586-020-2761-3. Epub 2020 Sep 23. Nature. 2020. PMID: 32968273 Free PMC article.

5

The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

Park JE, Keller GA, Ferrara N. Park JE, et al. Mol Biol Cell. 1993 Dec;4(12):1317-26. doi: 10.1091/mbc.4.12.1317. Mol Biol Cell. 1993. PMID: 8167412 Free PMC article.

6

Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

Gerber HP, Condorelli F, Park J, Ferrara N. Gerber HP, et al. Among authors: park j. J Biol Chem. 1997 Sep 19;272(38):23659-67. doi: 10.1074/jbc.272.38.23659. J Biol Chem. 1997. PMID: 9295307 Free article.

7

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.

Park JE, Chen HH, Winer J, Houck KA, Ferrara N. Park JE, et al. J Biol Chem. 1994 Oct 14;269(41):25646-54. J Biol Chem. 1994. PMID: 7929268 Free article.

8

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis.

Keyt BA, Nguyen HV, Berleau LT, Duarte CM, Park J, Chen H, Ferrara N. Keyt BA, et al. Among authors: park j. J Biol Chem. 1996 Mar 8;271(10):5638-46. doi: 10.1074/jbc.271.10.5638. J Biol Chem. 1996. PMID: 8621427 Free article.

9

Detection of water proximity to tryptophan residues in proteins by single photon radioluminescence.

Bicknese S, Zimet D, Park J, van Hoek AN, Shohet SB, Verkman AS. Bicknese S, et al. Among authors: park j. Biophys Chem. 1995 May;54(3):279-90. doi: 10.1016/0301-4622(94)00127-6. Biophys Chem. 1995. PMID: 7749062

10

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.

Amen AM, Fellmann C, Soczek KM, Ren SM, Lew RJ, Knott GJ, Park JE, McKinney AM, Mancini A, Doudna JA, Costello JF. Amen AM, et al. Among authors: park je. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2008772118. doi: 10.1073/pnas.2008772118. Proc Natl Acad Sci U S A. 2021. PMID: 33758097 Free PMC article.

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