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Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of hypoxia-inducible factor-1alpha and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway.
Jin HO, An S, Lee HC, Woo SH, Seo SK, Choe TB, Yoo DH, Lee SB, Um HD, Lee SJ, Park MJ, Kim JI, Hong SI, Rhee CH, Park IC. Jin HO, et al. Among authors: park mj, park ic. Cell Signal. 2007 Jul;19(7):1393-403. doi: 10.1016/j.cellsig.2006.12.014. Epub 2007 Jan 20. Cell Signal. 2007. PMID: 17307335
Paclitaxel stimulates chromosomal fusion and instability in cells with dysfunctional telomeres: implication in multinucleation and chemosensitization.
Park JE, Woo SR, Kang CM, Juhn KM, Ju YJ, Shin HJ, Joo HY, Park ER, Park IC, Hong SH, Hwang SG, Lee JK, Kim HK, Cho MH, Park GH, Lee KH. Park JE, et al. Among authors: park gh, park er, park ic. Biochem Biophys Res Commun. 2011 Jan 14;404(2):615-21. doi: 10.1016/j.bbrc.2010.12.018. Epub 2010 Dec 7. Biochem Biophys Res Commun. 2011. PMID: 21144828
Cells with dysfunctional telomeres are susceptible to reactive oxygen species hydrogen peroxide via generation of multichromosomal fusions and chromosomal fragments bearing telomeres.
Woo SR, Park JE, Juhn KM, Ju YJ, Jeong J, Kang CM, Yun HJ, Yun MY, Shin HJ, Joo HY, Park ER, Park IC, Hong SH, Hwang SG, Kim H, Cho MH, Kim SH, Park GH, Lee KH. Woo SR, et al. Among authors: park gh, park er, park je, park ic. Biochem Biophys Res Commun. 2012 Jan 6;417(1):204-10. doi: 10.1016/j.bbrc.2011.11.086. Epub 2011 Nov 25. Biochem Biophys Res Commun. 2012. PMID: 22138403
Akt is negatively regulated by the MULAN E3 ligase.
Bae S, Kim SY, Jung JH, Yoon Y, Cha HJ, Lee H, Kim K, Kim J, An IS, Kim J, Um HD, Park IC, Lee SJ, Nam SY, Jin YW, Lee JH, An S. Bae S, et al. Among authors: park ic. Cell Res. 2012 May;22(5):873-85. doi: 10.1038/cr.2012.38. Epub 2012 Mar 13. Cell Res. 2012. PMID: 22410793 Free PMC article.
531 results