Park HG - Search Results

1

Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer.

Byun WS, Kim WK, Han HJ, Chung HJ, Jang K, Kim HS, Kim S, Kim D, Bae ES, Park S, Lee J, Park HG, Lee SK. Byun WS, et al. Among authors: park hg, park s. Mol Ther Oncolytics. 2019 Oct 1;15:140-152. doi: 10.1016/j.omto.2019.09.005. eCollection 2019 Dec 20. Mol Ther Oncolytics. 2019. PMID: 31720371 Free PMC article.

2

Efficient synthesis and biological activity of Psammaplin A and its analogues as antitumor agents.

Hong S, Shin Y, Jung M, Ha MW, Park Y, Lee YJ, Shin J, Oh KB, Lee SK, Park HG. Hong S, et al. Among authors: park hg, park y. Eur J Med Chem. 2015;96:218-30. doi: 10.1016/j.ejmech.2015.04.001. Epub 2015 Apr 6. Eur J Med Chem. 2015. PMID: 25884112

3

Inhibition of DOT1L by Half-Selenopsammaplin A Analogs Suppresses Tumor Growth and EMT-Mediated Metastasis in Triple-Negative Breast Cancer.

Byun WS, Lee GH, Park HG, Lee SK. Byun WS, et al. Among authors: park hg. Pharmaceuticals (Basel). 2020 Dec 28;14(1):18. doi: 10.3390/ph14010018. Pharmaceuticals (Basel). 2020. PMID: 33379275 Free PMC article.

4

Synthesis and biological activity of selenopsammaplin A and its analogues as antitumor agents with DOT1L inhibitory activity.

Ju Han H, Sub Byun W, Ho Lee G, Kyung Kim W, Jang K, Yang S, Yang J, Woo Ha M, Hong S, Lee J, Shin J, Bong Oh K, Kook Lee S, Park HG. Ju Han H, et al. Among authors: park hg. Bioorg Med Chem. 2021 Apr 1;35:116072. doi: 10.1016/j.bmc.2021.116072. Epub 2021 Feb 11. Bioorg Med Chem. 2021. PMID: 33636429

5

Discovery of 2-((R)-4-(2-Fluoro-4-(methylsulfonyl)phenyl)-2-methylpiperazin-1-yl)-N-((1R,2s,3S,5S,7S)-5-hydroxyadamantan-2-yl)pyrimidine-4-carboxamide (SKI2852): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1).

Ryu JH, Lee JA, Kim S, Shin YA, Yang J, Han HY, Son HJ, Kim YH, Sa JH, Kim JS, Lee J, Lee J, Park HG. Ryu JH, et al. Among authors: park hg. J Med Chem. 2016 Nov 23;59(22):10176-10189. doi: 10.1021/acs.jmedchem.6b01122. Epub 2016 Nov 7. J Med Chem. 2016. PMID: 27798827

6

Determination and validation of psammaplin A and its derivatives in rat plasma by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study.

Lee JY, Lee MY, Ha MW, Won TH, Cho HJ, Shin J, Park HG, Kim DD. Lee JY, et al. Among authors: park hg. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 1;1000:155-62. doi: 10.1016/j.jchromb.2015.07.014. Epub 2015 Jul 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26232561

7

An α-quaternary chiral latam derivative, YH-304 as a novel broad-spectrum anticancer agent.

Hwang SJ, Park HG, Park Y, Lee HJ. Hwang SJ, et al. Among authors: park hg, park y. Int J Oncol. 2016 Dec;49(6):2480-2486. doi: 10.3892/ijo.2016.3726. Epub 2016 Oct 11. Int J Oncol. 2016. PMID: 27748805

8

Anti-cancer effect of GV1001 for prostate cancer: function as a ligand of GnRHR.

Kim JW, Yadav DK, Kim SJ, Lee MY, Park JM, Kim BS, Kim MH, Park HG, Kang KW. Kim JW, et al. Among authors: park hg, park jm. Endocr Relat Cancer. 2019 Feb;26(2):147-162. doi: 10.1530/ERC-18-0454. Endocr Relat Cancer. 2019. PMID: 30400054

9

Chemistry-oriented synthesis (ChOS) and target deconvolution on neuroprotective effect of a novel scaffold, oxaza spiroquinone.

Venkanna A, Cho KH, Dhorma LP, Kumar DN, Hah JM, Park HG, Kim SY, Kim MH. Venkanna A, et al. Among authors: park hg. Eur J Med Chem. 2019 Feb 1;163:453-480. doi: 10.1016/j.ejmech.2018.11.037. Epub 2018 Nov 29. Eur J Med Chem. 2019. PMID: 30530196

10

Inhibition of Streptococcus mutans adhesion and biofilm formation with small-molecule inhibitors of sortase A from Juniperus chinensis.

Cho E, Hwang JY, Park JS, Oh D, Oh DC, Park HG, Shin J, Oh KB. Cho E, et al. Among authors: park hg, park js. J Oral Microbiol. 2022 Jun 14;14(1):2088937. doi: 10.1080/20002297.2022.2088937. eCollection 2022. J Oral Microbiol. 2022. PMID: 35756538 Free PMC article.

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