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1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors.
Tavares MT, Krüger A, Yan SLR, Waitman KB, Gomes VM, de Oliveira DS, Paz F, Hilscher S, Schutkowski M, Sippl W, Ruiz C, Toledo MFZJ, Hassimotto NMA, Machado-Neto JA, Poso A, Cameron MD, Bannister TD, Palmisano G, Wrenger C, Kronenberger T, Parise-Filho R. Tavares MT, et al. Among authors: parise filho r. Sci Rep. 2023 Nov 29;13(1):21006. doi: 10.1038/s41598-023-47959-z. Sci Rep. 2023. PMID: 38030668 Free PMC article.
Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors.
Tavares MT, de Almeida LC, Kronenberger T, Monteiro Ferreira G, Fujii de Divitiis T, Franco Zannini Junqueira Toledo M, Mariko Aymoto Hassimotto N, Agostinho Machado-Neto J, Veras Costa-Lotufo L, Parise-Filho R. Tavares MT, et al. Among authors: parise filho r. Bioorg Med Chem. 2021 Apr 1;35:116085. doi: 10.1016/j.bmc.2021.116085. Epub 2021 Feb 23. Bioorg Med Chem. 2021. PMID: 33668008
HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents.
Waitman KB, de Almeida LC, Primi MC, Carlos JAEG, Ruiz C, Kronenberger T, Laufer S, Goettert MI, Poso A, Vassiliades SV, de Souza VAM, Toledo MFZJ, Hassimotto NMA, Cameron MD, Bannister TD, Costa-Lotufo LV, Machado-Neto JA, Tavares MT, Parise-Filho R. Waitman KB, et al. Among authors: parise filho r. Eur J Med Chem. 2024 Jan 5;263:115935. doi: 10.1016/j.ejmech.2023.115935. Epub 2023 Nov 10. Eur J Med Chem. 2024. PMID: 37989057
N-[(1,3-Benzodioxol-5-yl)meth-yl]benzene-sulfonamide: an analogue of capsaicin.
Maganhi SH, Tavares MT, Damião MC, Parise Filho R. Maganhi SH, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Oct 23;69(Pt 11):o1700. doi: 10.1107/S1600536813028481. eCollection 2013 Oct 23. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 24454126 Free PMC article.
Peppers: A "Hot" Natural Source for Antitumor Compounds.
Cunha MR, Tavares MT, Fernandes TB, Parise-Filho R. Cunha MR, et al. Among authors: parise filho r. Molecules. 2021 Mar 10;26(6):1521. doi: 10.3390/molecules26061521. Molecules. 2021. PMID: 33802144 Free PMC article. Review.
28 results