Pardons M - Search Results

1

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.

Pardons M, Baxter AE, Massanella M, Pagliuzza A, Fromentin R, Dufour C, Leyre L, Routy JP, Kaufmann DE, Chomont N. Pardons M, et al. PLoS Pathog. 2019 Feb 27;15(2):e1007619. doi: 10.1371/journal.ppat.1007619. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30811499 Free PMC article.

2

Latency-Reversing Agents Induce Differential Responses in Distinct Memory CD4 T Cell Subsets in Individuals on Antiretroviral Therapy.

Pardons M, Fromentin R, Pagliuzza A, Routy JP, Chomont N. Pardons M, et al. Cell Rep. 2019 Nov 26;29(9):2783-2795.e5. doi: 10.1016/j.celrep.2019.10.101. Cell Rep. 2019. PMID: 31775045 Free PMC article.

3

Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART.

Gantner P, Pagliuzza A, Pardons M, Ramgopal M, Routy JP, Fromentin R, Chomont N. Gantner P, et al. Among authors: pardons m. Nat Commun. 2020 Aug 14;11(1):4089. doi: 10.1038/s41467-020-17898-8. Nat Commun. 2020. PMID: 32796830 Free PMC article.

4

In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia.

Cole B, Lambrechts L, Gantner P, Noppe Y, Bonine N, Witkowski W, Chen L, Palmer S, Mullins JI, Chomont N, Pardons M, Vandekerckhove L. Cole B, et al. Among authors: pardons m. Nat Commun. 2021 Jun 17;12(1):3727. doi: 10.1038/s41467-021-24080-1. Nat Commun. 2021. PMID: 34140517 Free PMC article.

5

The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription.

Okoye AA, Fromentin R, Takata H, Brehm JH, Fukazawa Y, Randall B, Pardons M, Tai V, Tang J, Smedley J, Axthelm M, Lifson JD, Picker LJ, Favre D, Trautmann L, Chomont N. Okoye AA, et al. Among authors: pardons m. PLoS Pathog. 2022 Jan 18;18(1):e1010245. doi: 10.1371/journal.ppat.1010245. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35041707 Free PMC article.

6

First-in-human immunoPET imaging of HIV-1 infection using ⁸⁹Zr-labeled VRC01 broadly neutralizing antibody.

Beckford-Vera DR, Flavell RR, Seo Y, Martinez-Ortiz E, Aslam M, Thanh C, Fehrman E, Pardons M, Kumar S, Deitchman AN, Ravanfar V, Schulte B, Wu IK, Pan T, Reeves JD, Nixon CC, Iyer NS, Torres L, Munter SE, Hyunh T, Petropoulos CJ, Hoh R, Franc BL, Gama L, Koup RA, Mascola JR, Chomont N, Deeks SG, VanBrocklin HF, Henrich TJ. Beckford-Vera DR, et al. Among authors: pardons m. Nat Commun. 2022 Mar 9;13(1):1219. doi: 10.1038/s41467-022-28727-5. Nat Commun. 2022. PMID: 35264559 Free PMC article.

7

HIV rapidly targets a diverse pool of CD4⁺ T cells to establish productive and latent infections.

Gantner P, Buranapraditkun S, Pagliuzza A, Dufour C, Pardons M, Mitchell JL, Kroon E, Sacdalan C, Tulmethakaan N, Pinyakorn S, Robb ML, Phanuphak N, Ananworanich J, Hsu D, Vasan S, Trautmann L, Fromentin R, Chomont N. Gantner P, et al. Among authors: pardons m. Immunity. 2023 Mar 14;56(3):653-668.e5. doi: 10.1016/j.immuni.2023.01.030. Epub 2023 Feb 17. Immunity. 2023. PMID: 36804957 Free PMC article.

8

Phenotypic characterization of single CD4+ T cells harboring genetically intact and inducible HIV genomes.

Dufour C, Richard C, Pardons M, Massanella M, Ackaoui A, Murrell B, Routy B, Thomas R, Routy JP, Fromentin R, Chomont N. Dufour C, et al. Among authors: pardons m. Nat Commun. 2023 Feb 27;14(1):1115. doi: 10.1038/s41467-023-36772-x. Nat Commun. 2023. PMID: 36849523 Free PMC article.

9

Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1.

Bouchat S, Delacourt N, Kula A, Darcis G, Van Driessche B, Corazza F, Gatot JS, Melard A, Vanhulle C, Kabeya K, Pardons M, Avettand-Fenoel V, Clumeck N, De Wit S, Rohr O, Rouzioux C, Van Lint C. Bouchat S, et al. Among authors: pardons m. EMBO Mol Med. 2016 Feb 1;8(2):117-38. doi: 10.15252/emmm.201505557. EMBO Mol Med. 2016. PMID: 26681773 Free PMC article.

10

Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir.

Pardons M, Cole B, Lambrechts L, van Snippenberg W, Rutsaert S, Noppe Y, De Langhe N, Dhondt A, Vega J, Eyassu F, Nijs E, Van Gulck E, Boden D, Vandekerckhove L. Pardons M, et al. Nat Commun. 2023 Dec 18;14(1):8397. doi: 10.1038/s41467-023-44020-5. Nat Commun. 2023. PMID: 38110433 Free PMC article.

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