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Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis.
Barcena-Varela M, Paish H, Alvarez L, Uriarte I, Latasa MU, Santamaria E, Recalde M, Garate M, Claveria A, Colyn L, Arechederra M, Iraburu MJ, Milkiewicz M, Milkiewicz P, Sangro B, Robinson SM, French J, Pardo-Saganta A, Oyarzabal J, Prosper F, Rombouts K, Oakley F, Mann J, Berasain C, Avila MA, G Fernandez-Barrena M. Barcena-Varela M, et al. Among authors: pardo saganta a. Gut. 2021 Feb;70(2):388-400. doi: 10.1136/gutjnl-2019-320205. Epub 2020 Apr 23. Gut. 2021. PMID: 32327527
Notch3 Deficiency Attenuates Pulmonary Fibrosis and Impedes Lung-Function Decline.
Vera L, Garcia-Olloqui P, Petri E, Viñado AC, Valera PS, Blasco-Iturri Z, Calvo IA, Cenzano I, Ruppert C, Zulueta JJ, Prosper F, Saez B, Pardo-Saganta A. Vera L, et al. Among authors: pardo saganta a. Am J Respir Cell Mol Biol. 2021 Apr;64(4):465-476. doi: 10.1165/rcmb.2020-0516OC. Am J Respir Cell Mol Biol. 2021. PMID: 33493092
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Viñado AC, Calvo IA, Cenzano I, Olaverri D, Cocera M, San Martin-Uriz P, Romero JP, Vilas-Zornoza A, Vera L, Gomez-Cebrian N, Puchades-Carrasco L, Lisi-Vega LE, Apaolaza I, Valera P, Guruceaga E, Granero-Molto F, Ripalda-Cemborain P, Luck TJ, Bullinger L, Planes FJ, Rifon JJ, Méndez-Ferrer S, Yusuf RZ, Pardo-Saganta A, Prosper F, Saez B. Viñado AC, et al. Among authors: pardo saganta a. Leukemia. 2022 Aug;36(8):1969-1979. doi: 10.1038/s41375-022-01601-5. Epub 2022 May 26. Leukemia. 2022. PMID: 35618797 Free PMC article.
Parent stem cells can serve as niches for their daughter cells.
Pardo-Saganta A, Tata PR, Law BM, Saez B, Chow RD, Prabhu M, Gridley T, Rajagopal J. Pardo-Saganta A, et al. Nature. 2015 Jul 30;523(7562):597-601. doi: 10.1038/nature14553. Epub 2015 Jul 6. Nature. 2015. PMID: 26147083 Free PMC article.
CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata.
Causton B, Pardo-Saganta A, Gillis J, Discipio K, Kooistra T, Rajagopal J, Xavier RJ, Cho JL, Medoff BD. Causton B, et al. Among authors: pardo saganta a. Am J Respir Cell Mol Biol. 2018 Dec;59(6):684-694. doi: 10.1165/rcmb.2017-0181OC. Am J Respir Cell Mol Biol. 2018. PMID: 29958012 Free PMC article.
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