Pardo O - Search Results

1

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B. Swanton C, et al. Among authors: pardo o. Cancer Cell. 2007 Jun;11(6):498-512. doi: 10.1016/j.ccr.2007.04.011. Cancer Cell. 2007. PMID: 17560332 Free article.

2

Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function.

Khalil MI, Ismail HM, Panasyuk G, Bdzhola A, Filonenko V, Gout I, Pardo OE. Khalil MI, et al. Among authors: pardo oe. Int J Mol Sci. 2023 May 15;24(10):8806. doi: 10.3390/ijms24108806. Int J Mol Sci. 2023. PMID: 37240151 Free PMC article.

3

Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis.

Pardo OE, Arcaro A, Salerno G, Raguz S, Downward J, Seckl MJ. Pardo OE, et al. J Biol Chem. 2002 Apr 5;277(14):12040-6. doi: 10.1074/jbc.M109006200. Epub 2002 Jan 28. J Biol Chem. 2002. PMID: 11815602 Free article. Retracted.

4

Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells.

Pardo OE, Lesay A, Arcaro A, Lopes R, Ng BL, Warne PH, McNeish IA, Tetley TD, Lemoine NR, Mehmet H, Seckl MJ, Downward J. Pardo OE, et al. Mol Cell Biol. 2003 Nov;23(21):7600-10. doi: 10.1128/MCB.23.21.7600-7610.2003. Mol Cell Biol. 2003. PMID: 14560006 Free PMC article.

5

CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness.

Michl P, Ramjaun AR, Pardo OE, Warne PH, Wagner M, Poulsom R, D'Arrigo C, Ryder K, Menke A, Gress T, Downward J. Michl P, et al. Cancer Cell. 2005 Jun;7(6):521-32. doi: 10.1016/j.ccr.2005.05.018. Cancer Cell. 2005. PMID: 15950902 Free article.

6

Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling.

Khanzada UK, Pardo OE, Meier C, Downward J, Seckl MJ, Arcaro A. Khanzada UK, et al. Among authors: pardo oe. Oncogene. 2006 Feb 9;25(6):877-87. doi: 10.1038/sj.onc.1209117. Oncogene. 2006. PMID: 16170339

7

Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.

Katso RM, Pardo OE, Palamidessi A, Franz CM, Marinov M, De Laurentiis A, Downward J, Scita G, Ridley AJ, Waterfield MD, Arcaro A. Katso RM, et al. Mol Biol Cell. 2006 Sep;17(9):3729-44. doi: 10.1091/mbc.e05-11-1083. Epub 2006 Jun 14. Mol Biol Cell. 2006. PMID: 16775008 Free PMC article.

8

FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2.

Pardo OE, Wellbrock C, Khanzada UK, Aubert M, Arozarena I, Davidson S, Bowen F, Parker PJ, Filonenko VV, Gout IT, Sebire N, Marais R, Downward J, Seckl MJ. Pardo OE, et al. EMBO J. 2006 Jul 12;25(13):3078-88. doi: 10.1038/sj.emboj.7601198. Epub 2006 Jun 29. EMBO J. 2006. PMID: 16810323 Free PMC article.

9

An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis.

Lara R, Mauri FA, Taylor H, Derua R, Shia A, Gray C, Nicols A, Shiner RJ, Schofield E, Bates PA, Waelkens E, Dallman M, Lamb J, Zicha D, Downward J, Seckl MJ, Pardo OE. Lara R, et al. Among authors: pardo oe. Oncogene. 2011 Aug 11;30(32):3513-21. doi: 10.1038/onc.2011.61. Epub 2011 Mar 21. Oncogene. 2011. PMID: 21423205

10

Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer.

Li H, Stokes W, Chater E, Roy R, de Bruin E, Hu Y, Liu Z, Smit EF, Heynen GJ, Downward J, Seckl MJ, Wang Y, Tang H, Pardo OE. Li H, et al. Cell Discov. 2016 Sep 27;2:16031. doi: 10.1038/celldisc.2016.31. eCollection 2016. Cell Discov. 2016. PMID: 27721983 Free PMC article.

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