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Granzyme A-producing T helper cells are critical for acute graft-versus-host disease.
Park S, Griesenauer B, Jiang H, Adom D, Mehrpouya-Bahrami P, Chakravorty S, Kazemian M, Imam T, Srivastava R, Hayes TA, Pardo J, Janga SC, Paczesny S, Kaplan MH, Olson MR. Park S, et al. Among authors: pardo j. JCI Insight. 2020 Sep 17;5(18):e124465. doi: 10.1172/jci.insight.124465. JCI Insight. 2020. PMID: 32809971 Free PMC article.
Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.
Santiago L, Menaa C, Arias M, Martin P, Jaime-Sánchez P, Metkar S, Comas L, Erill N, Gonzalez-Rumayor V, Esser E, Galvez EM, Raja S, Simon MM, Sprague SM, Gabay C, Martinez-Lostao L, Pardo J, Froelich CJ. Santiago L, et al. Among authors: pardo j. Arthritis Rheumatol. 2017 Feb;69(2):320-334. doi: 10.1002/art.39857. Arthritis Rheumatol. 2017. PMID: 27598995
Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
Santiago L, Castro M, Sanz-Pamplona R, Garzón M, Ramirez-Labrada A, Tapia E, Moreno V, Layunta E, Gil-Gómez G, Garrido M, Peña R, Lanuza PM, Comas L, Jaime-Sanchez P, Uranga-Murillo I, Del Campo R, Pelegrín P, Camerer E, Martínez-Lostao L, Muñoz G, Uranga JA, Alcalde A, Galvez EM, Ferrandez A, Bird PI, Metkar S, Arias MA, Pardo J. Santiago L, et al. Among authors: pardo j. Cell Rep. 2020 Jul 7;32(1):107847. doi: 10.1016/j.celrep.2020.107847. Cell Rep. 2020. PMID: 32640217 Free article.
Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.
Garzón-Tituaña M, Sierra-Monzón JL, Comas L, Santiago L, Khaliulina-Ushakova T, Uranga-Murillo I, Ramirez-Labrada A, Tapia E, Morte-Romea E, Algarate S, Couty L, Camerer E, Bird PI, Seral C, Luque P, Paño-Pardo JR, Galvez EM, Pardo J, Arias M. Garzón-Tituaña M, et al. Among authors: pardo j. Theranostics. 2021 Jan 30;11(8):3781-3795. doi: 10.7150/thno.49288. eCollection 2021. Theranostics. 2021. PMID: 33664861 Free PMC article.
Biological relevance of Granzymes A and K during E. coli sepsis.
Uranga-Murillo I, Tapia E, Garzón-Tituaña M, Ramirez-Labrada A, Santiago L, Pesini C, Esteban P, Roig FJ, Galvez EM, Bird PI, Pardo J, Arias M. Uranga-Murillo I, et al. Among authors: pardo j. Theranostics. 2021 Oct 17;11(20):9873-9883. doi: 10.7150/thno.59418. eCollection 2021. Theranostics. 2021. PMID: 34815792 Free PMC article.
Noncytotoxic Roles of Granzymes in Health and Disease.
Richardson KC, Jung K, Pardo J, Turner CT, Granville DJ. Richardson KC, et al. Among authors: pardo j. Physiology (Bethesda). 2022 Nov 1;37(6):323-348. doi: 10.1152/physiol.00011.2022. Epub 2022 Jul 12. Physiology (Bethesda). 2022. PMID: 35820180 Free article. Review.
1,045 results