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ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation.
Ragagnin AMG, Sundaramoorthy V, Farzana F, Gautam S, Saravanabavan S, Takalloo Z, Mehta P, Do-Ha D, Parakh S, Shadfar S, Hunter J, Vidal M, Jagaraj CJ, Brocardo M, Konopka A, Yang S, Rayner SL, Williams KL, Blair IP, Chung RS, Lee A, Ooi L, Atkin JD. Ragagnin AMG, et al. Among authors: parakh s. Sci Rep. 2023 Nov 22;13(1):20467. doi: 10.1038/s41598-023-46802-9. Sci Rep. 2023. PMID: 37993492 Free PMC article.
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress.
Halloran M, Ragagnin AMG, Vidal M, Parakh S, Yang S, Heng B, Grima N, Shahheydari H, Soo KY, Blair I, Guillemin GJ, Sundaramoorthy V, Atkin JD. Halloran M, et al. Among authors: parakh s. Cell Mol Life Sci. 2020 Oct;77(19):3859-3873. doi: 10.1007/s00018-019-03394-w. Epub 2019 Dec 4. Cell Mol Life Sci. 2020. PMID: 31802140
118 results