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Production of the antimalarial drug precursor artemisinic acid in engineered yeast.
Nature. 2006 Apr 13;440(7086):940-3. doi: 10.1038/nature04640.
Nature. 2006.
PMID: 16612385
High-level production of amorpha-4,11-diene in a two-phase partitioning bioreactor of metabolically engineered Escherichia coli.
Newman JD, Marshall J, Chang M, Nowroozi F, Paradise E, Pitera D, Newman KL, Keasling JD.
Newman JD, et al.
Biotechnol Bioeng. 2006 Nov 5;95(4):684-91. doi: 10.1002/bit.21017.
Biotechnol Bioeng. 2006.
PMID: 16878333
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Engineering triterpene production in Saccharomyces cerevisiae-beta-amyrin synthase from Artemisia annua.
Kirby J, Romanini DW, Paradise EM, Keasling JD.
Kirby J, et al. Among authors: paradise em.
FEBS J. 2008 Apr;275(8):1852-9. doi: 10.1111/j.1742-4658.2008.06343.x. Epub 2008 Mar 8.
FEBS J. 2008.
PMID: 18336574
Free article.
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Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids.
Shiba Y, Paradise EM, Kirby J, Ro DK, Keasling JD.
Shiba Y, et al. Among authors: paradise em.
Metab Eng. 2007 Mar;9(2):160-8. doi: 10.1016/j.ymben.2006.10.005. Epub 2006 Nov 17.
Metab Eng. 2007.
PMID: 17196416
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Redirection of flux through the FPP branch-point in Saccharomyces cerevisiae by down-regulating squalene synthase.
Paradise EM, Kirby J, Chan R, Keasling JD.
Paradise EM, et al.
Biotechnol Bioeng. 2008 Jun 1;100(2):371-8. doi: 10.1002/bit.21766.
Biotechnol Bioeng. 2008.
PMID: 18175359
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Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid.
Ro DK, Ouellet M, Paradise EM, Burd H, Eng D, Paddon CJ, Newman JD, Keasling JD.
Ro DK, et al. Among authors: paradise em.
BMC Biotechnol. 2008 Nov 4;8:83. doi: 10.1186/1472-6750-8-83.
BMC Biotechnol. 2008.
PMID: 18983675
Free PMC article.
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