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Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Liang SH, Chen JM, Normandin MD, Chang JS, Chang GC, Taylor CK, Trapa P, Plummer MS, Para KS, Conn EL, Lopresti-Morrow L, Lanyon LF, Cook JM, Richter KE, Nolan CE, Schachter JB, Janat F, Che Y, Shanmugasundaram V, Lefker BA, Enerson BE, Livni E, Wang L, Guehl NJ, Patnaik D, Wagner FF, Perlis R, Holson EB, Haggarty SJ, El Fakhri G, Kurumbail RG, Vasdev N. Liang SH, et al. Among authors: para ks. Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9601-5. doi: 10.1002/anie.201603797. Epub 2016 Jun 29. Angew Chem Int Ed Engl. 2016. PMID: 27355874 Free PMC article.
Demoralization in Parkinson disease.
Koo BB, Chow CA, Shah DR, Khan FH, Steinberg B, Derlein D, Nalamada K, Para KS, Kakade VM, Patel AS, de Figueiredo JM, Louis ED. Koo BB, et al. Among authors: para ks. Neurology. 2018 May 1;90(18):e1613-e1617. doi: 10.1212/WNL.0000000000005425. Epub 2018 Apr 4. Neurology. 2018. PMID: 29618626 Free PMC article.
Design of peptidomimetic ligands for the pp60src SH2 domain.
Plummer MS, Lunney EA, Para KS, Shahripour A, Stankovic CJ, Humblet C, Fergus JH, Marks JS, Herrera R, Hubbell S, Saltiel A, Sawyer TK. Plummer MS, et al. Among authors: para ks. Bioorg Med Chem. 1997 Jan;5(1):41-7. doi: 10.1016/s0968-0896(96)00200-3. Bioorg Med Chem. 1997. PMID: 9043656 No abstract available.
Discovery and optimization of nonpeptide HIV-1 protease inhibitors.
Tummino PJ, Prasad JV, Ferguson D, Nouhan C, Graham N, Domagala JM, Ellsworth E, Gajda C, Hagen SE, Lunney EA, Para KS, Tait BD, Pavlovsky A, Erickson JW, Gracheck S, McQuade TJ, Hupe DJ. Tummino PJ, et al. Among authors: para ks. Bioorg Med Chem. 1996 Sep;4(9):1401-10. doi: 10.1016/0968-0896(96)00134-4. Bioorg Med Chem. 1996. PMID: 8894098
Nonpeptidic HIV protease inhibitors: 4-hydroxy-pyran-2-one inhibitors with functional tethers to P1 phenyl ring to reach S3 pocket of the enzyme.
Vara Prasad J, Tummino PJ, Ferguson D, Saunders J, Vander Roest S, McQuade TJ, Heldsinger A, Reyner EL, Stewart BH, Guttendorf RJ, Para KS, Lunney EA, Gracheck SJ, Domagala JM. Vara Prasad J, et al. Among authors: para ks. Biochem Biophys Res Commun. 1996 Apr 25;221(3):815-20. doi: 10.1006/bbrc.1996.0679. Biochem Biophys Res Commun. 1996. PMID: 8630044
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