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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Deprez-Poulain R, Hennuyer N, Bosc D, Liang WG, Enée E, Marechal X, Charton J, Totobenazara J, Berte G, Jahklal J, Verdelet T, Dumont J, Dassonneville S, Woitrain E, Gauriot M, Paquet C, Duplan I, Hermant P, Cantrelle FX, Sevin E, Culot M, Landry V, Herledan A, Piveteau C, Lippens G, Leroux F, Tang WJ, van Endert P, Staels B, Deprez B. Deprez-Poulain R, et al. Among authors: paquet c. Nat Commun. 2015 Sep 23;6:8250. doi: 10.1038/ncomms9250. Nat Commun. 2015. PMID: 26394692 Free PMC article.
The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.
Hennuyer N, Duplan I, Paquet C, Vanhoutte J, Woitrain E, Touche V, Colin S, Vallez E, Lestavel S, Lefebvre P, Staels B. Hennuyer N, et al. Among authors: paquet c. Atherosclerosis. 2016 Jun;249:200-8. doi: 10.1016/j.atherosclerosis.2016.03.003. Epub 2016 Mar 4. Atherosclerosis. 2016. PMID: 27108950
Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.
Woldt E, Sebti Y, Solt LA, Duhem C, Lancel S, Eeckhoute J, Hesselink MK, Paquet C, Delhaye S, Shin Y, Kamenecka TM, Schaart G, Lefebvre P, Nevière R, Burris TP, Schrauwen P, Staels B, Duez H. Woldt E, et al. Among authors: paquet c. Nat Med. 2013 Aug;19(8):1039-46. doi: 10.1038/nm.3213. Epub 2013 Jul 14. Nat Med. 2013. PMID: 23852339 Free PMC article.
p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Cudejko C, Wouters K, Fuentes L, Hannou SA, Paquet C, Bantubungi K, Bouchaert E, Vanhoutte J, Fleury S, Remy P, Tailleux A, Chinetti-Gbaguidi G, Dombrowicz D, Staels B, Paumelle R. Cudejko C, et al. Among authors: paquet c. Blood. 2011 Sep 1;118(9):2556-66. doi: 10.1182/blood-2010-10-313106. Epub 2011 Jun 2. Blood. 2011. PMID: 21636855 Free PMC article.
Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development.
Wouters K, Cudejko C, Gijbels MJ, Fuentes L, Bantubungi K, Vanhoutte J, Dièvart R, Paquet C, Bouchaert E, Hannou SA, Gizard F, Tailleux A, de Winther MP, Staels B, Paumelle R. Wouters K, et al. Among authors: paquet c. PLoS One. 2012;7(3):e32440. doi: 10.1371/journal.pone.0032440. Epub 2012 Mar 5. PLoS One. 2012. PMID: 22403661 Free PMC article.
Psychosis in Neurodegenerative Dementias: A Systematic Comparative Review.
Cressot C, Vrillon A, Lilamand M, Francisque H, Méauzoone A, Hourregue C, Dumurgier J, Marlinge E, Paquet C, Cognat E. Cressot C, et al. Among authors: paquet c. J Alzheimers Dis. 2024;99(1):85-99. doi: 10.3233/JAD-231363. J Alzheimers Dis. 2024. PMID: 38669539
Clinical value of plasma ALZpath pTau217 immunoassay for assessing mild cognitive impairment.
Lehmann S, Schraen-Maschke S, Vidal JS, Delaby C, Buee L, Blanc F, Paquet C, Allinquant B, Bombois S, Gabelle A, Hanon O; BALTAZAR study group. Lehmann S, et al. Among authors: paquet c. J Neurol Neurosurg Psychiatry. 2024 Apr 24:jnnp-2024-333467. doi: 10.1136/jnnp-2024-333467. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 38658136 Free article.
465 results