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Page 1
Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500).
Black WC, Abdoli A, An X, Auger A, Beaulieu P, Bernatchez M, Caron C, Chefson A, Crane S, Diallo M, Dorich S, Fader LD, Ferraro GB, Fournier S, Gao Q, Ginzburg Y, Hamel M, Han Y, Jones P, Lanoix S, Lacbay CM, Leclaire ME, Levy M, Mamane Y, Mulani A, Papp R, Pellerin C, Picard A, Skeldon A, Skorey K, Stocco R, St-Onge M, Truchon JF, Truong VL, Zimmermann M, Zinda M, Roulston A. Black WC, et al. Among authors: papp r. J Med Chem. 2024 Feb 22;67(4):2349-2368. doi: 10.1021/acs.jmedchem.3c01917. Epub 2024 Feb 1. J Med Chem. 2024. PMID: 38299539
Predicting the survival benefit of cardiac resynchronization therapy with defibrillator function for non-ischemic heart failure-Role of the Goldenberg risk score.
Merkel ED, Schwertner WR, Behon A, Kuthi L, Veres B, Osztheimer I, Papp R, Molnár L, Zima E, Gellér L, Kosztin A, Merkely B. Merkel ED, et al. Among authors: papp r. Front Cardiovasc Med. 2023 Jan 10;9:1062094. doi: 10.3389/fcvm.2022.1062094. eCollection 2022. Front Cardiovasc Med. 2023. PMID: 36704467 Free PMC article.
Prolactin-Releasing Peptide Contributes to Stress-Related Mood Disorders and Inhibits Sleep/Mood Regulatory Melanin-Concentrating Hormone Neurons in Rats.
Vas S, Papp RS, Könczöl K, Bogáthy E, Papp N, Ádori C, Durst M, Sípos K, Ocskay K, Farkas I, Bálint F, Ferenci S, Török B, Kovács A, Szabó E, Zelena D, Kovács KJ, Földes A, Kató E, Köles L, Bagdy G, Palkovits M, Tóth ZE. Vas S, et al. Among authors: papp rs. J Neurosci. 2023 Feb 1;43(5):846-862. doi: 10.1523/JNEUROSCI.2139-21.2022. Epub 2022 Dec 23. J Neurosci. 2023. PMID: 36564184 Free PMC article.
Closed loop stimulation in patients with chronic heart failure and severe chronotropic incompetence: Responders versus non-responders.
Proff J, Merkely B, Papp R, Lenz C, Nordbeck P, Butter C, Meyhoefer J, Doering M, MacCarter D, Ingel K, Wolfarth B, Thouet T, Landmesser U, Roser M. Proff J, et al. Among authors: papp r. Int J Cardiol. 2023 Jan 1;370:222-228. doi: 10.1016/j.ijcard.2022.10.019. Epub 2022 Oct 13. Int J Cardiol. 2023. PMID: 36243181 Clinical Trial.
Subclinical leaflet thrombosis after transcatheter aortic valve implantation is associated with silent brain injury on brain magnetic resonance imaging.
Apor A, Bartykowszki A, Szilveszter B, Varga A, Suhai FI, Manouras A, Molnár L, Jermendy ÁL, Panajotu A, Turáni MF, Papp R, Karády J, Kolossváry M, Kováts T, Maurovich-Horvat P, Merkely B, Nagy AI. Apor A, et al. Among authors: papp r. Eur Heart J Cardiovasc Imaging. 2022 Nov 17;23(12):1584-1595. doi: 10.1093/ehjci/jeac191. Eur Heart J Cardiovasc Imaging. 2022. PMID: 36168113
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
Bubenik M, Mader P, Mochirian P, Vallée F, Clark J, Truchon JF, Perryman AL, Pau V, Kurinov I, Zahn KE, Leclaire ME, Papp R, Mathieu MC, Hamel M, Duffy NM, Godbout C, Casas-Selves M, Falgueyret JP, Baruah PS, Nicolas O, Stocco R, Poirier H, Martino G, Fortin AB, Roulston A, Chefson A, Dorich S, St-Onge M, Patel P, Pellerin C, Ciblat S, Pinter T, Barabé F, El Bakkouri M, Parikh P, Gervais C, Sfeir A, Mamane Y, Morris SJ, Black WC, Sicheri F, Gallant M. Bubenik M, et al. Among authors: papp r. J Med Chem. 2022 Oct 13;65(19):13198-13215. doi: 10.1021/acs.jmedchem.2c00998. Epub 2022 Sep 20. J Med Chem. 2022. PMID: 36126059 Free PMC article.
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
Szychowski J, Papp R, Dietrich E, Liu B, Vallée F, Leclaire ME, Fourtounis J, Martino G, Perryman AL, Pau V, Yin SY, Mader P, Roulston A, Truchon JF, Marshall CG, Diallo M, Duffy NM, Stocco R, Godbout C, Bonneau-Fortin A, Kryczka R, Bhaskaran V, Mao D, Orlicky S, Beaulieu P, Turcotte P, Kurinov I, Sicheri F, Mamane Y, Gallant M, Black WC. Szychowski J, et al. Among authors: papp r. J Med Chem. 2022 Aug 11;65(15):10251-10284. doi: 10.1021/acs.jmedchem.2c00552. Epub 2022 Jul 26. J Med Chem. 2022. PMID: 35880755 Free PMC article.
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Gallo D, Young JTF, Fourtounis J, Martino G, Álvarez-Quilón A, Bernier C, Duffy NM, Papp R, Roulston A, Stocco R, Szychowski J, Veloso A, Alam H, Baruah PS, Fortin AB, Bowlan J, Chaudhary N, Desjardins J, Dietrich E, Fournier S, Fugère-Desjardins C, Goullet de Rugy T, Leclaire ME, Liu B, Bhaskaran V, Mamane Y, Melo H, Nicolas O, Singhania A, Szilard RK, Tkáč J, Yin SY, Morris SJ, Zinda M, Marshall CG, Durocher D. Gallo D, et al. Among authors: papp r. Nature. 2022 Apr;604(7907):749-756. doi: 10.1038/s41586-022-04638-9. Epub 2022 Apr 20. Nature. 2022. PMID: 35444283 Free PMC article.
93 results