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Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a prospective multicentre cohort study.
Staessen JA, Wendt R, Yu YL, Kalbitz S, Thijs L, Siwy J, Raad J, Metzger J, Neuhaus B, Papkalla A, von der Leyen H, Mebazaa A, Dudoignon E, Spasovski G, Milenkova M, Canevska-Taneska A, Salgueira Lazo M, Psichogiou M, Rajzer MW, Fuławka Ł, Dzitkowska-Zabielska M, Weiss G, Feldt T, Stegemann M, Normark J, Zoufaly A, Schmiedel S, Seilmaier M, Rumpf B, Banasik M, Krajewska M, Catanese L, Rupprecht HD, Czerwieńska B, Peters B, Nilsson Å, Rothfuss K, Lübbert C, Mischak H, Beige J; CRIT-CoV-U investigators. Staessen JA, et al. Among authors: papkalla a. Lancet Digit Health. 2022 Oct;4(10):e727-e737. doi: 10.1016/S2589-7500(22)00150-9. Epub 2022 Aug 31. Lancet Digit Health. 2022. PMID: 36057526 Free PMC article.
A multicenter prospective, randomized, placebo-controlled phase II/III trial for preemptive acute graft-versus-host disease therapy.
Weissinger EM, Metzger J, Schleuning M, Schmid C, Messinger D, Beutel G, Wagner-Drouet EM, Schetelig J, Baurmann H, Rank A, Stolzl F, Schäfer-Eckart K, Westphal K, Bethge W, von Harsdorf S, Bunjes DW, Heidenreich D, Klein S, Holler E, Kreipe HH, Jonigk D, Türüchanow I, Raad J, Papkalla A, von der Leyen H, Hambach L, Hamwi I, Ehrlich S, Krauter J, Stadler M, Ganser A. Weissinger EM, et al. Among authors: papkalla a. Leukemia. 2021 Jun;35(6):1763-1772. doi: 10.1038/s41375-020-01059-3. Epub 2020 Oct 20. Leukemia. 2021. PMID: 33082512 Free PMC article. Clinical Trial.
Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a prospective multicentre cohort study.
Staessen JA, Wendt R, Yu YL, Kalbitz S, Thijs L, Siwy J, Raad J, Metzger J, Neuhaus B, Papkalla A, von der Leyen H, Mebazaa A, Dudoignon E, Spasovski G, Milenkova M, Canevska-Taneska A, Salgueira Lazo M, Psichogiou M, Rajzer MW, Fuławka Ł, Dzitkowska-Zabielska M, Weiss G, Feldt T, Stegemann M, Normark J, Zoufaly A, Schmiedel S, Seilmaier M, Rumpf B, Banasik M, Krajewska M, Catanese L, Rupprecht HD, Czerwieńska B, Peters B, Nilsson Å, Rothfuss K, Lübbert C, Mischak H, Beige J; CRIT-CoV-U investigators. Staessen JA, et al. Among authors: papkalla a. Lancet Digit Health. 2022 Oct;4(10):e727-e737. doi: 10.1016/S2589-7500(22)00150-9. Epub 2022 Aug 31. Lancet Digit Health. 2022. PMID: 36057526 Free PMC article.
Ledipasvir plus sofosbuvir fixed-dose combination for 6 weeks in patients with acute hepatitis C virus genotype 1 monoinfection (HepNet Acute HCV IV): an open-label, single-arm, phase 2 study.
Deterding K, Spinner CD, Schott E, Welzel TM, Gerken G, Klinker H, Spengler U, Wiegand J, Schulze Zur Wiesch J, Pathil A, Cornberg M, Umgelter A, Zöllner C, Zeuzem S, Papkalla A, Weber K, Hardtke S, von der Leyen H, Koch A, von Witzendorff D, Manns MP, Wedemeyer H; HepNet Acute HCV IV Study Group. Deterding K, et al. Among authors: papkalla a. Lancet Infect Dis. 2017 Feb;17(2):215-222. doi: 10.1016/S1473-3099(16)30408-X. Epub 2016 Oct 28. Lancet Infect Dis. 2017. PMID: 28029529 Clinical Trial.
Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial).
Krauter J, Fiedler W, Schlenk RF, Paschka P, Thol F, Lübbert M, Wattad M, Verbeek M, Könecke C, Neuhaus B, Papkalla A, Kebenko M, Janning M, Döhner K, Gaidzik VI, Becker H, Greil C, Reimer P, Götze KS, Döhner H, Ganser A, Heuser M. Krauter J, et al. Among authors: papkalla a. Br J Haematol. 2018 Oct;183(2):235-241. doi: 10.1111/bjh.15546. Br J Haematol. 2018. PMID: 30378121 Free article. Clinical Trial.
Sofosbuvir monotherapy fails to achieve HEV RNA elimination in patients with chronic hepatitis E - The HepNet SofE pilot study.
Cornberg M, Pischke S, Müller T, Behrendt P, Piecha F, Benckert J, Todt D, Steinmann E, Papkalla A, von Karpowitz M, Koch A, Lohse A, Hardtke S, Manns MP, Wedemeyer H. Cornberg M, et al. Among authors: papkalla a. J Hepatol. 2020 Sep;73(3):696-699. doi: 10.1016/j.jhep.2020.05.020. Epub 2020 Jul 2. J Hepatol. 2020. PMID: 32624195 Clinical Trial. No abstract available.
Hemofiltrate CC chemokine 1[9-74] causes effective internalization of CCR5 and is a potent inhibitor of R5-tropic human immunodeficiency virus type 1 strains in primary T cells and macrophages.
Münch J, Ständker L, Pöhlmann S, Baribaud F, Papkalla A, Rosorius O, Stauber R, Sass G, Heveker N, Adermann K, Escher S, Klüver E, Doms RW, Forssmann WG, Kirchhoff F. Münch J, et al. Among authors: papkalla a. Antimicrob Agents Chemother. 2002 Apr;46(4):982-90. doi: 10.1128/AAC.46.4.982-990.2002. Antimicrob Agents Chemother. 2002. PMID: 11897579 Free PMC article.
Amino acid 324 in the simian immunodeficiency virus SIVmac V3 loop can confer CD4 independence and modulate the interaction with CCR5 and alternative coreceptors.
Pöhlmann S, Davis C, Meister S, Leslie GJ, Otto C, Reeves JD, Puffer BA, Papkalla A, Krumbiegel M, Marzi A, Lorenz S, Münch J, Doms RW, Kirchhoff F. Pöhlmann S, et al. Among authors: papkalla a. J Virol. 2004 Apr;78(7):3223-32. doi: 10.1128/jvi.78.7.3223-3232.2004. J Virol. 2004. PMID: 15016843 Free PMC article.