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Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
J Med Chem. 2023 Nov 9;66(21):14787-14814. doi: 10.1021/acs.jmedchem.3c01385. Epub 2023 Oct 30.
J Med Chem. 2023.
PMID: 37902787
Free PMC article.
Melatonin-vorinostat hybrid ligands show higher histone deacetylase and cancer cell growth inhibition than vorinostat.
Helmi YY, Papenkordt N, Rennar G, Gbahou F, El-Hady AK, Labani N, Schmidtkunz K, Boettcher S, Jockers R, Abdel-Halim M, Jung M, Zlotos DP.
Helmi YY, et al. Among authors: papenkordt n.
Arch Pharm (Weinheim). 2023 Sep;356(9):e2300149. doi: 10.1002/ardp.202300149. Epub 2023 Jun 20.
Arch Pharm (Weinheim). 2023.
PMID: 37339785
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Total synthesis and biological evaluation of histone deacetylase inhibitor WF-3161.
Kohr M, Papenkordt N, Jung M, Kazmaier U.
Kohr M, et al. Among authors: papenkordt n.
Org Biomol Chem. 2023 May 31;21(21):4382-4387. doi: 10.1039/d3ob00641g.
Org Biomol Chem. 2023.
PMID: 37194325
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