Papadopoulos N - Search Results

1

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms.

Pecquet C, Papadopoulos N, Balligand T, Chachoua I, Tisserand A, Vertenoeil G, Nédélec A, Vertommen D, Roy A, Marty C, Nivarthi H, Defour JP, El-Khoury M, Hug E, Majoros A, Xu E, Zagrijtschuk O, Fertig TE, Marta DS, Gisslinger H, Gisslinger B, Schalling M, Casetti I, Rumi E, Pietra D, Cavalloni C, Arcaini L, Cazzola M, Komatsu N, Kihara Y, Sunami Y, Edahiro Y, Araki M, Lesyk R, Buxhofer-Ausch V, Heibl S, Pasquier F, Havelange V, Plo I, Vainchenker W, Kralovics R, Constantinescu SN. Pecquet C, et al. Among authors: papadopoulos n. Blood. 2023 Feb 23;141(8):917-929. doi: 10.1182/blood.2022016846. Blood. 2023. PMID: 36356299 Free PMC article.

2

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization.

Perrin F, Papadopoulos N, Suelves N, Opsomer R, Vadukul DM, Vrancx C, Smith SO, Vertommen D, Kienlen-Campard P, Constantinescu SN. Perrin F, et al. Among authors: papadopoulos n. iScience. 2020 Dec 2;23(12):101887. doi: 10.1016/j.isci.2020.101887. eCollection 2020 Dec 18. iScience. 2020. PMID: 33367225 Free PMC article.

3

Functional Consequences of Mutations in Myeloproliferative Neoplasms.

Constantinescu SN, Vainchenker W, Levy G, Papadopoulos N. Constantinescu SN, et al. Among authors: papadopoulos n. Hemasphere. 2021 Jun 1;5(6):e578. doi: 10.1097/HS9.0000000000000578. eCollection 2021 Jun. Hemasphere. 2021. PMID: 34095761 Free PMC article. Review.

4

Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation.

Papadopoulos N, Nédélec A, Derenne A, Şulea TA, Pecquet C, Chachoua I, Vertenoeil G, Tilmant T, Petrescu AJ, Mazzucchelli G, Iorga BI, Vertommen D, Constantinescu SN. Papadopoulos N, et al. Nat Commun. 2023 Apr 5;14(1):1881. doi: 10.1038/s41467-023-37277-3. Nat Commun. 2023. PMID: 37019903 Free PMC article.

5

SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice.

Willekens C, Laplane L, Dagher T, Benlabiod C, Papadopoulos N, Lacout C, Rameau P, Catelain C, Alfaro A, Edmond V, Signolle N, Marchand V, Droin N, Hoogenboezem R, Schneider RK, Penson A, Abdel-Wahab O, Giraudier S, Pasquier F, Marty C, Plo I, Villeval JL, Constantinescu SN, Porteu F, Vainchenker W, Solary E. Willekens C, et al. Among authors: papadopoulos n. Leukemia. 2023 Jun;37(6):1287-1297. doi: 10.1038/s41375-023-01878-0. Epub 2023 Apr 26. Leukemia. 2023. PMID: 37100881

6

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers.

Defour JP, Leroy E, Dass S, Balligand T, Levy G, Brett IC, Papadopoulos N, Mouton C, Genet L, Pecquet C, Staerk J, Smith SO, Constantinescu SN. Defour JP, et al. Among authors: papadopoulos n. Elife. 2023 Jun 20;12:e81521. doi: 10.7554/eLife.81521. Elife. 2023. PMID: 37338955 Free PMC article.

7

Modulation of human thrombopoietin receptor conformations uncouples JAK2 V617F-driven activation from cytokine-induced stimulation.

Papadopoulos N, Pristavec A, Nédélec A, Levy G, Staerk J, Constantinescu SN. Papadopoulos N, et al. Blood. 2023 Nov 23;142(21):1818-1830. doi: 10.1182/blood.2022019580. Blood. 2023. PMID: 37616564

8

Novel germline JAK2^R715T mutation causing PV-like erythrocytosis in 3 generations. Amelioration by Ropeg-Interferon.

Song J, Lanikova L, Kim SJ, Papadopoulos N, Meznarich J, Constantinescu SN, Parsegov B, Prchal JF, Prchal JT. Song J, et al. Among authors: papadopoulos n. Am J Hematol. 2024 Apr 17. doi: 10.1002/ajh.27311. Online ahead of print. Am J Hematol. 2024. PMID: 38629639

9

Erratum: Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization.

Perrin F, Papadopoulos N, Suelves N, Opsomer R, Vadukul DM, Vrancx C, Smith SO, Vertommen D, Kienlen-Campard P, Constantinescu SN. Perrin F, et al. Among authors: papadopoulos n. iScience. 2021 Jan 23;24(2):102057. doi: 10.1016/j.isci.2021.102057. eCollection 2021 Feb 19. iScience. 2021. PMID: 33554063 Free PMC article.

10

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates.

Papadopoulos N, Suelves N, Perrin F, Vadukul DM, Vrancx C, Constantinescu SN, Kienlen-Campard P. Papadopoulos N, et al. Biomedicines. 2022 Oct 29;10(11):2753. doi: 10.3390/biomedicines10112753. Biomedicines. 2022. PMID: 36359274 Free PMC article. Review.

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