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Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids.
Abdullah MO, Zeng RX, Margerum CL, Papadopoli D, Monnin C, Punter KB, Chu C, Al-Rofaidi M, Al-Tannak NF, Berardi D, Rattray Z, Rattray NJW, Abraham SA, Eskelinen EL, Watson DG, Avizonis D, Topisirovic I, Chan EYW. Abdullah MO, et al. Among authors: papadopoli d. Cell Rep. 2022 Aug 16;40(7):111198. doi: 10.1016/j.celrep.2022.111198. Cell Rep. 2022. PMID: 35977476 Free article.
The role of GSK3 in metabolic pathway perturbations in cancer.
Papadopoli D, Pollak M, Topisirovic I. Papadopoli D, et al. Biochim Biophys Acta Mol Cell Res. 2021 Jul;1868(8):119059. doi: 10.1016/j.bbamcr.2021.119059. Epub 2021 May 12. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33989699 Free article. Review.
Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells.
Benslimane Y, Bertomeu T, Coulombe-Huntington J, McQuaid M, Sánchez-Osuna M, Papadopoli D, Avizonis D, Russo MST, Huard C, Topisirovic I, Wurtele H, Tyers M, Harrington L. Benslimane Y, et al. Among authors: papadopoli d. Mol Cell. 2020 Sep 3;79(5):846-856.e8. doi: 10.1016/j.molcel.2020.07.010. Epub 2020 Aug 4. Mol Cell. 2020. PMID: 32755594 Free article.
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.
Uchenunu O, Zhdanov AV, Hutton P, Jovanovic P, Wang Y, Andreev DE, Hulea L, Papadopoli DJ, Avizonis D, Baranov PV, Pollak MN, Papkovsky DB, Topisirovic I. Uchenunu O, et al. Among authors: papadopoli dj. FEBS Open Bio. 2022 May;12(5):959-982. doi: 10.1002/2211-5463.13398. Epub 2022 Apr 1. FEBS Open Bio. 2022. PMID: 35302710 Free PMC article.
Cancer Plasticity: The Role of mRNA Translation.
Lee LJ, Papadopoli D, Jewer M, Del Rincon S, Topisirovic I, Lawrence MG, Postovit LM. Lee LJ, et al. Among authors: papadopoli d. Trends Cancer. 2021 Feb;7(2):134-145. doi: 10.1016/j.trecan.2020.09.005. Epub 2020 Oct 13. Trends Cancer. 2021. PMID: 33067172 Free PMC article. Review.
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK.
Tan C, Ginzberg MB, Webster R, Iyengar S, Liu S, Papadopoli D, Concannon J, Wang Y, Auld DS, Jenkins JL, Rost H, Topisirovic I, Hilfinger A, Derry WB, Patel N, Kafri R. Tan C, et al. Among authors: papadopoli d. Dev Cell. 2021 Jun 21;56(12):1756-1769.e7. doi: 10.1016/j.devcel.2021.04.030. Epub 2021 May 21. Dev Cell. 2021. PMID: 34022133 Free article.
mTOR as a central regulator of lifespan and aging.
Papadopoli D, Boulay K, Kazak L, Pollak M, Mallette FA, Topisirovic I, Hulea L. Papadopoli D, et al. F1000Res. 2019 Jul 2;8:F1000 Faculty Rev-998. doi: 10.12688/f1000research.17196.1. eCollection 2019. F1000Res. 2019. PMID: 31316753 Free PMC article. Review.
A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Igelmann S, Lessard F, Uchenunu O, Bouchard J, Fernandez-Ruiz A, Rowell MC, Lopes-Paciencia S, Papadopoli D, Fouillen A, Ponce KJ, Huot G, Mignacca L, Benfdil M, Kalegari P, Wahba HM, Pencik J, Vuong N, Quenneville J, Guillon J, Bourdeau V, Hulea L, Gagnon E, Kenner L, Moriggl R, Nanci A, Pollak MN, Omichinski JG, Topisirovic I, Ferbeyre G. Igelmann S, et al. Among authors: papadopoli d. Mol Cell. 2021 Sep 16;81(18):3848-3865.e19. doi: 10.1016/j.molcel.2021.08.028. Mol Cell. 2021. PMID: 34547241 Free article.
18 results