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The PTEN⁻PI3K Axis in Cancer.
Papa A, Pandolfi PP. Papa A, et al. Biomolecules. 2019 Apr 17;9(4):153. doi: 10.3390/biom9040153. Biomolecules. 2019. PMID: 30999672 Free PMC article. Review.
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.
Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP. Lee YR, et al. Among authors: papa a. Science. 2019 May 17;364(6441):eaau0159. doi: 10.1126/science.aau0159. Science. 2019. PMID: 31097636 Free PMC article.
PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Srijakotre N, Liu HJ, Nobis M, Man J, Yip HYK, Papa A, Abud HE, Anderson KI, Welch HCE, Tiganis T, Timpson P, McLean CA, Ooms LM, Mitchell CA. Srijakotre N, et al. Among authors: papa a. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28056-28067. doi: 10.1073/pnas.2006445117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097662 Free PMC article.
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer.
Rodgers SJ, Ooms LM, Oorschot VMJ, Schittenhelm RB, Nguyen EV, Hamila SA, Rynkiewicz N, Gurung R, Eramo MJ, Sriratana A, Fedele CG, Caramia F, Loi S, Kerr G, Abud HE, Ramm G, Papa A, Ellisdon AM, Daly RJ, McLean CA, Mitchell CA. Rodgers SJ, et al. Among authors: papa a. Nat Commun. 2021 May 25;12(1):3140. doi: 10.1038/s41467-021-23241-6. Nat Commun. 2021. PMID: 34035258 Free PMC article.
PTEN in Immunity.
Papa A, Pandolfi PP. Papa A, et al. Curr Top Microbiol Immunol. 2022;436:95-115. doi: 10.1007/978-3-031-06566-8_4. Curr Top Microbiol Immunol. 2022. PMID: 36243841
Pills of PTEN? In and out for tumor suppression.
Papa A, Chen M, Pandolfi PP. Papa A, et al. Cell Res. 2013 Oct;23(10):1155-6. doi: 10.1038/cr.2013.103. Epub 2013 Aug 6. Cell Res. 2013. PMID: 23917528 Free PMC article.
1,017 results