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New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells.
Ottanà R, Maccari R, Amuso S, Wolber G, Schuster D, Herdlinger S, Manao G, Camici G, Paoli P. Ottanà R, et al. Among authors: paoli p. Eur J Med Chem. 2012 Apr;50:332-43. doi: 10.1016/j.ejmech.2012.02.012. Epub 2012 Feb 21. Eur J Med Chem. 2012. PMID: 22381357
Acylphosphatase is a strong apoptosis inducer in HeLa cell line.
Giannoni E, Cirri P, Paoli P, Fiaschi T, Camici G, Manao G, Raugei G, Ramponi G. Giannoni E, et al. Among authors: paoli p. Mol Cell Biol Res Commun. 2000 May;3(5):264-70. doi: 10.1006/mcbr.2000.0228. Mol Cell Biol Res Commun. 2000. PMID: 10964749
453 results