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The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor.
Mol Oncol. 2022 Feb;16(3):630-647. doi: 10.1002/1878-0261.13101. Epub 2021 Sep 28.
Mol Oncol. 2022.
PMID: 34520622
Free PMC article.
SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma.
Carreno G, Boult JKR, Apps J, Gonzalez-Meljem JM, Haston S, Guiho R, Stache C, Danielson LS, Koers A, Smith LM, Virasami A, Panousopoulos L, Buchfelder M, Jacques TS, Chesler L, Robinson SP, Martinez-Barbera JP.
Carreno G, et al. Among authors: panousopoulos l.
Endocr Relat Cancer. 2019 Mar;26(3):355-366. doi: 10.1530/ERC-18-0538.
Endocr Relat Cancer. 2019.
PMID: 30645190
Free PMC article.
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Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors.
Carreno G, Apps JR, Lodge EJ, Panousopoulos L, Haston S, Gonzalez-Meljem JM, Hahn H, Andoniadou CL, Martinez-Barbera JP.
Carreno G, et al. Among authors: panousopoulos l.
Development. 2017 Sep 15;144(18):3289-3302. doi: 10.1242/dev.153387. Epub 2017 Aug 14.
Development. 2017.
PMID: 28807898
Free PMC article.
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MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma.
Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, Gonzalez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques TS, Andoniadou CL, Martinez-Barbera JP.
Haston S, et al. Among authors: panousopoulos l.
Development. 2017 Jun 15;144(12):2141-2152. doi: 10.1242/dev.150490. Epub 2017 May 15.
Development. 2017.
PMID: 28506993
Free PMC article.
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Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.
Gonzalez-Meljem JM, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Mousavy-Gharavy SN, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Martinez-Barbera JP.
Gonzalez-Meljem JM, et al. Among authors: panousopoulos l.
Nat Commun. 2017 Nov 28;8(1):1819. doi: 10.1038/s41467-017-01992-5.
Nat Commun. 2017.
PMID: 29180744
Free PMC article.
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Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse.
Xavier GM, Panousopoulos L, Cobourne MT.
Xavier GM, et al. Among authors: panousopoulos l.
PLoS One. 2013;8(1):e55274. doi: 10.1371/journal.pone.0055274. Epub 2013 Jan 29.
PLoS One. 2013.
PMID: 23383134
Free PMC article.
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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston S, Gonzalez-Gualda E, Morsli S, Ge J, Reen V, Calderwood A, Moutsopoulos I, Panousopoulos L, Deletic P, Carreno G, Guiho R, Manshaei S, Gonzalez-Meljem JM, Lim HY, Simpson DJ, Birch J, Pallikonda HA, Chandra T, Macias D, Doherty GJ, Rassl DM, Rintoul RC, Signore M, Mohorianu I, Akbar AN, Gil J, Muñoz-Espín D, Martinez-Barbera JP.
Haston S, et al. Among authors: panousopoulos l.
Cancer Cell. 2023 Jul 10;41(7):1242-1260.e6. doi: 10.1016/j.ccell.2023.05.004. Epub 2023 Jun 1.
Cancer Cell. 2023.
PMID: 37267953
Free article.
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