Panousis C - Search Results

1

Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?

Jaffar J, McMillan L, Wilson N, Panousis C, Hardy C, Cho HJ, Symons K, Glaspole I, Westall G, Wong M. Jaffar J, et al. Among authors: panousis c. Am J Physiol Lung Cell Mol Physiol. 2022 Feb 1;322(2):L258-L272. doi: 10.1152/ajplung.00165.2021. Epub 2021 Dec 7. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 34873957 Free article.

2

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors.

Panousis C, Dhagat U, Edwards KM, Rayzman V, Hardy MP, Braley H, Gauvreau GM, Hercus TR, Smith S, Sehmi R, McMillan L, Dottore M, McClure BJ, Fabri LJ, Vairo G, Lopez AF, Parker MW, Nash AD, Wilson NJ, Wilson MJ, Owczarek CM. Panousis C, et al. MAbs. 2016;8(3):436-53. doi: 10.1080/19420862.2015.1119352. Epub 2015 Dec 14. MAbs. 2016. PMID: 26651396 Free PMC article.

3

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.

Göbel K, Pankratz S, Asaridou CM, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG. Göbel K, et al. Among authors: panousis c. Nat Commun. 2016 May 18;7:11626. doi: 10.1038/ncomms11626. Nat Commun. 2016. PMID: 27188843 Free PMC article.

4

Factor XII blockade inhibits aortic dilatation in angiotensin II-infused apolipoprotein E-deficient mice.

Moran CS, Seto SW, Biros E, Krishna SM, Morton SK, Kleinschnitz C, Panousis C, Golledge J. Moran CS, et al. Among authors: panousis c. Clin Sci (Lond). 2020 May 15;134(9):1049-1061. doi: 10.1042/CS20191020. Clin Sci (Lond). 2020. PMID: 32309850

5

Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC.

Busfield SJ, Biondo M, Wong M, Ramshaw HS, Lee EM, Ghosh S, Braley H, Panousis C, Roberts AW, He SZ, Thomas D, Fabri L, Vairo G, Lock RB, Lopez AF, Nash AD. Busfield SJ, et al. Among authors: panousis c. Leukemia. 2014 Nov;28(11):2213-21. doi: 10.1038/leu.2014.128. Epub 2014 Apr 7. Leukemia. 2014. PMID: 24705479

6

Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.

Beck S, Stegner D, Loroch S, Baig AA, Göb V, Schumbrutzki C, Eilers E, Sickmann A, May F, Nolte MW, Panousis C, Nieswandt B. Beck S, et al. Among authors: panousis c. J Thromb Haemost. 2021 Nov;19(11):2835-2840. doi: 10.1111/jth.15488. Epub 2021 Aug 19. J Thromb Haemost. 2021. PMID: 34363738 Free article.

7

A phase I, first-in-human, randomized dose-escalation study of anti-activated factor XII monoclonal antibody garadacimab.

McKenzie A, Roberts A, Malandkar S, Feuersenger H, Panousis C, Pawaskar D. McKenzie A, et al. Among authors: panousis c. Clin Transl Sci. 2022 Mar;15(3):626-637. doi: 10.1111/cts.13180. Epub 2021 Dec 3. Clin Transl Sci. 2022. PMID: 34859955 Free PMC article. Clinical Trial.

8

HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure.

Ow SY, Kapp EA, Tomasetig V, Zalewski A, Simmonds J, Panousis C, Wilson MJ, Nash AD, Pelzing M. Ow SY, et al. Among authors: panousis c. MAbs. 2023 Jan-Dec;15(1):2163459. doi: 10.1080/19420862.2022.2163459. MAbs. 2023. PMID: 36628468 Free PMC article.

9

Activated Coagulation FXII: A Unique Target for In Vivo Molecular Imaging.

Walsh APG, Yu E, McFadyen JD, Bongcaron V, Moon MJ, Huang A, Arthur JF, Muir IL, Rayzman V, Panousis C, Wang X, Peter K. Walsh APG, et al. Among authors: panousis c. Arterioscler Thromb Vasc Biol. 2023 Jun;43(6):1031-1040. doi: 10.1161/ATVBAHA.122.318883. Epub 2023 Apr 20. Arterioscler Thromb Vasc Biol. 2023. PMID: 37078286

10

The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats.

Krupka J, May F, Weimer T, Pragst I, Kleinschnitz C, Stoll G, Panousis C, Dickneite G, Nolte MW. Krupka J, et al. Among authors: panousis c. PLoS One. 2016 Jan 27;11(1):e0146783. doi: 10.1371/journal.pone.0146783. eCollection 2016. PLoS One. 2016. PMID: 26815580 Free PMC article.

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