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Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.
Changelian PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O'Shea JJ, Borie DC. Changelian PS, et al. Among authors: paniagua r. Science. 2003 Oct 31;302(5646):875-8. doi: 10.1126/science.1087061. Science. 2003. PMID: 14593182
Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in nonhuman primates.
Borie DC, Changelian PS, Larson MJ, Si MS, Paniagua R, Higgins JP, Holm B, Campbell A, Lau M, Zhang S, Flores MG, Rousvoal G, Hawkins J, Ball DA, Kudlacz EM, Brissette WH, Elliott EA, Reitz BA, Morris RE. Borie DC, et al. Among authors: paniagua r. Transplantation. 2005 Apr 15;79(7):791-801. doi: 10.1097/01.tp.0000157117.30290.6f. Transplantation. 2005. PMID: 15818321
Hyperacute rejection of hDAF-transgenic pig organ xenografts in cynomolgus monkeys: influence of pre-existing anti-pig antibodies and prevention by the alpha GAL glycoconjugate GAS914.
Lam TT, Hausen B, Boeke-Purkis K, Paniagua R, Lau M, Hook L, Berry G, Higgins J, Duthaler RO, Katopodis AG, Robbins R, Reitz B, Borie D, Schuurman HJ, Morris RE. Lam TT, et al. Among authors: paniagua r. Xenotransplantation. 2004 Nov;11(6):517-24. doi: 10.1111/j.1399-3089.2004.00173.x. Xenotransplantation. 2004. PMID: 15479461
Anti-pig antibody levels in non-human primates of various origin.
Lam TT, Boeke-Purkis K, Lau M, Paniagua R, Schuurman HJ, Morris RE. Lam TT, et al. Among authors: paniagua r. Xenotransplantation. 2004 Jul;11(4):332-9. doi: 10.1111/j.1399-3089.2004.00139.x. Xenotransplantation. 2004. PMID: 15196127
399 results