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Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.
Shi W, Vu T, Boucher D, Biernacka A, Nde J, Pandita RK, Straube J, Boyle GM, Al-Ejeh F, Nag P, Jeffery J, Harris JL, Bain AL, Grzelak M, Skrzypczak M, Mitra A, Dojer N, Crosetto N, Cloonan N, Becherel OJ, Finnie J, Skaar JR, Walkley CR, Pandita TK, Rowicka M, Ginalski K, Lane SW, Khanna KK. Shi W, et al. Among authors: pandita tk, pandita rk. Blood. 2017 May 4;129(18):2479-2492. doi: 10.1182/blood-2016-06-725093. Epub 2017 Mar 7. Blood. 2017. PMID: 28270450 Free PMC article.
Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation.
Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Sharma GG, et al. Among authors: pandita tk, pandita rk. Mol Cell Biol. 2003 Nov;23(22):8363-76. doi: 10.1128/MCB.23.22.8363-8376.2003. Mol Cell Biol. 2003. PMID: 14585993 Free PMC article.
Involvement of human MOF in ATM function.
Gupta A, Sharma GG, Young CS, Agarwal M, Smith ER, Paull TT, Lucchesi JC, Khanna KK, Ludwig T, Pandita TK. Gupta A, et al. Among authors: pandita tk. Mol Cell Biol. 2005 Jun;25(12):5292-305. doi: 10.1128/MCB.25.12.5292-5305.2005. Mol Cell Biol. 2005. PMID: 15923642 Free PMC article.
Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.
Pandita RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, Chakhparonian M, Gupta A, Wellinger RJ, Zhang J, Powell SN, Roti Roti JL, Lieberman HB, Pandita TK. Pandita RK, et al. Among authors: pandita tk. Mol Cell Biol. 2006 Mar;26(5):1850-64. doi: 10.1128/MCB.26.5.1850-1864.2006. Mol Cell Biol. 2006. PMID: 16479004 Free PMC article.
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status.
Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, Gupta A, Rief N, Horikoshi N, Baskaran R, Lee JH, Löbrich M, Paull TT, Roti Roti JL, Pandita TK. Hunt CR, et al. Among authors: pandita tk, pandita rk. Cancer Res. 2007 Apr 1;67(7):3010-7. doi: 10.1158/0008-5472.CAN-06-4328. Cancer Res. 2007. PMID: 17409407
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis.
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. Gupta A, et al. Among authors: pandita s, pandita tk, pandita rk. Mol Cell Biol. 2008 Jan;28(1):397-409. doi: 10.1128/MCB.01045-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967868 Free PMC article.
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.
Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK. Richard DJ, et al. Among authors: pandita tk, pandita rk. Nature. 2008 May 29;453(7195):677-81. doi: 10.1038/nature06883. Epub 2008 Apr 30. Nature. 2008. PMID: 18449195
204 results