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Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.
Thyrell L, Hjortsberg L, Arulampalam V, Panaretakis T, Uhles S, Dagnell M, Zhivotovsky B, Leibiger I, Grandér D, Pokrovskaja K. Thyrell L, et al. Among authors: panaretakis t. J Biol Chem. 2004 Jun 4;279(23):24152-62. doi: 10.1074/jbc.M312219200. Epub 2004 Mar 31. J Biol Chem. 2004. PMID: 15056668 Free article.
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy.
Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J, Corcoran M, Björklund AC, Hultenby K, Lundin J, Heyman M, Söderhäll S, Mazur J, Porwit A, Pandolfi PP, Zhivotovsky B, Panaretakis T, Grandér D. Laane E, et al. Among authors: panaretakis t. Cell Death Differ. 2009 Jul;16(7):1018-29. doi: 10.1038/cdd.2009.46. Epub 2009 Apr 24. Cell Death Differ. 2009. PMID: 19390558
Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells.
Kharaziha P, Rodriguez P, Li Q, Rundqvist H, Björklund AC, Augsten M, Ullén A, Egevad L, Wiklund P, Nilsson S, Kroemer G, Grander D, Panaretakis T. Kharaziha P, et al. Among authors: panaretakis t. Cell Death Dis. 2012 Jan 26;3(1):e262. doi: 10.1038/cddis.2012.1. Cell Death Dis. 2012. PMID: 22278289 Free PMC article.
Back to Stockholm for 'metabolism, epigenetics and cell death'.
Panaretakis T, Joseph B, Zhivotovsky B. Panaretakis T, et al. Cell Death Differ. 2012 May;19(5):909-12. doi: 10.1038/cdd.2012.6. Epub 2012 Feb 3. Cell Death Differ. 2012. PMID: 22301918 Free PMC article. No abstract available.
Tumor cell-derived exosomes: a message in a bottle.
Kharaziha P, Ceder S, Li Q, Panaretakis T. Kharaziha P, et al. Among authors: panaretakis t. Biochim Biophys Acta. 2012 Aug;1826(1):103-11. doi: 10.1016/j.bbcan.2012.03.006. Epub 2012 Apr 1. Biochim Biophys Acta. 2012. PMID: 22503823 Review.
Sorafenib has potent antitumor activity against multiple myeloma in vitro, ex vivo, and in vivo in the 5T33MM mouse model.
Kharaziha P, De Raeve H, Fristedt C, Li Q, Gruber A, Johnsson P, Kokaraki G, Panzar M, Laane E, Osterborg A, Zhivotovsky B, Jernberg-Wiklund H, Grandér D, Celsing F, Björkholm M, Vanderkerken K, Panaretakis T. Kharaziha P, et al. Among authors: panaretakis t. Cancer Res. 2012 Oct 15;72(20):5348-62. doi: 10.1158/0008-5472.CAN-12-0658. Epub 2012 Sep 4. Cancer Res. 2012. PMID: 22952216
Multitargeted therapies for multiple myeloma.
Kharaziha P, Ceder S, Sanchez C, Panaretakis T. Kharaziha P, et al. Among authors: panaretakis t. Autophagy. 2013 Feb 1;9(2):255-7. doi: 10.4161/auto.22738. Epub 2012 Nov 26. Autophagy. 2013. PMID: 23183549 Free PMC article.
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